Merck
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文件

858143P

Avanti

1-油酰基-2-羟基-sn-甘油基-3-磷酸-L-丝氨酸（钠盐）

Avanti Polar Lipids

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别名:
1-(9Z-十八烷基)-sn-甘油-3-磷酸-L-丝氨酸（钠盐）；PS(18:1(9Z)/0:0); 18:1 LPS; C18:1 LPS; 110726
经验公式（希尔记法）:
C24H45NO9PNa
CAS号:
326589-90-6
分子量:
545.58

描述

1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium salt)

检测方案

99% (LPS; may contain up to 15% of the 2-LPS isomer, TLC)

形式

powder

包装

pkg of 1 × 10 mg (858143P-10mg)
pkg of 1 × 100 mg (858143P-100mg)
pkg of 1 × 25 mg (858143P-25mg)
pkg of 1 × 5 mg (858143P-5mg)
pkg of 1 × 50 mg (858143P-50mg)

manufacturer/tradename

Avanti Polar Lipids

lipid type

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES string

O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

应用

18:1 Lyso PS已被用于：
  • 制备磷脂小泡
  • 研究其对神经生长因子(NGF)诱导的丝裂原活化蛋白激酶(MAPK)和丝氨酸/苏氨酸蛋白激酶(Akt)信号的影响
  • 防止高基氏体中缺乏磷脂酰丝氨酸(PS)的从头合成

包装

5 mL透明玻璃密封安瓿（858143P-100mg）
5 mL透明玻璃密封安瓿（858143P-10mg）
5 mL透明玻璃密封安瓿（858143P-25mg）
5 mL透明玻璃密封安瓿（858143P-50mg）
5 mL透明玻璃密封安瓿（858143P-5mg）

储存分类代码

11 - Combustible Solids

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The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid
Varela Chavez C, et al.
Cellular Microbiology, 17(10), 1477-1493 (2015)
Suriakarthiga Ganesan et al.
Traffic (Copenhagen, Denmark), 20(3), 226-245 (2018-12-21)
Diacylglycerol (DAG) is a key signaling lipid and intermediate in lipid metabolism. Our knowledge of DAG distribution and dynamics in cell membranes is limited. Using live-cell fluorescence microscopy we investigated the localization of yeast cytosolic-facing pools of DAG in response
Takafumi Matsumura et al.
Scientific reports, 11(1), 3458-3458 (2021-02-12)
In vitro spermatogenesis (IVS) using air-liquid interphase organ culture method is possible with mouse testis tissues. The same method, however, has been hardly applicable to animals other than mice, only producing no or limited progression of spermatogenesis. In the present
Qingxin Shi et al.
Food & function, 10(12), 7782-7792 (2019-11-30)
Triterpenoid saponins from Kuding tea have demonstrated preventive effects on hyperlipidaemia induced by a high-fat diet. Lysoglycerophospholipids (Lyso-GPLs) are known to be associated with proatherogenic conditions such as hyperlipidaemia. In this study, a target profiling strategy based on a multiple
Wuhanqimuge et al.
FEBS open bio, 3, 243-251 (2013-06-19)
Lysophosphatidylcholine (LPC) is one of the major lysophospholipids mainly generated by phospholipase A2 (PLA2)-mediated hydrolysis of phosphatidylcholine (PC). We previously found that LPC displays neurotrophin-like activity in the rat pheochromocytoma PC12 cells and in cerebellar granule neurons, but the molecular
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