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Merck
CN

860353P

Avanti

16:0 PC-d13

Avanti Research - A Croda Brand

别名:

1,2-dipalmitoyl-sn-glycero-3-phosphocholine-1,1,2,2-d4-N,N,N-trimethyl-d9

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关于此项目

经验公式(希尔记法):
C40H67NO8PD13
化学文摘社编号:
分子量:
747.12
MDL number:
UNSPSC Code:
12352100
NACRES:
NA.25
Assay:
>99% (TLC)
Form:
powder
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产品名称

16:0 PC-d13, Avanti Research - A Croda Brand 860353P, powder

InChI

1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1/i3D3,4D3,5D3,34D2,35D2

InChI key

KILNVBDSWZSGLL-QZDIQHKFSA-N

SMILES string

[H][C@@](COP([O-])(OC([2H])([2H])C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (860353P-10mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860353P

shipped in

dry ice

storage temp.

−20°C

General description

16:0 PC-d13 is a deuterated phosphocholine (PC) in which 13 protons of dipalmitoyl are replaced by deuterium.

Application

16:0 PC-d13 has been used in the preparation of asymmetric large unilamellar vesicles (aLUVs) to measure lipid translocation.

Packaging

5 mL Amber Glass Screw Cap Vial (860353P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

wgk

WGK 3

法规信息

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分析证书(COA)

Lot/Batch Number

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1H NMR shows slow phospholipid flip-flop in gel and fluid bilayers
Marquardt D, et al.
Langmuir, 33(15) (2017)
Drew Marquardt et al.
Langmuir : the ACS journal of surfaces and colloids, 33(15), 3731-3741 (2017-01-21)
We measured the transbilayer diffusion of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) in large unilamellar vesicles, in both the gel (Lβ') and fluid (Lα) phases. The choline resonance of headgroup-protiated DPPC exchanged into the outer leaflet of headgroup-deuterated DPPC-d13 vesicles was monitored using 1H

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The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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