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860410C

Avanti

5-PAHSA-d9

Name: 5-PAHSA-d9
Brand: AVANTI

Avanti Research^™ - A Croda Brand

别名:

5-[((13,13,14,14,15,15,16,16,16-d9)palmitoyl)hydroxy]-stearic acid

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关于此项目

经验公式（希尔记法）:

C₃₄H₅₇D₉O₄

化学文摘社编号:

1809226-17-2

分子量:

547.94

UNSPSC Code:

12352211

NACRES:

NA.25

Assay:

>99% (TLC)

Form:

liquid

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属性

产品名称

5-PAHSA-d9, Avanti Research^™ - A Croda Brand 860410C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (860410C-1mg), pkg of 1 × 1 mL (860410C-500ug)

manufacturer/tradename

Avanti Research^™ - A Croda Brand 860410C

concentration

0.5 mg/mL (860410C-500ug), 1 mg/mL (860410C-1mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCC(OC(CCCCCCCCCCCC([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])=O)CCCC(O)=O

InChI

1S/C34H66O4/c1-3-5-7-9-11-13-15-16-18-20-22-24-26-31-34(37)38-32(29-27-30-33(35)36)28-25-23-21-19-17-14-12-10-8-6-4-2/h32H,3-31H2,1-2H3,(H,35,36)/i1D3,3D2,5D2,7D2

InChI key

QBGKCWKQYJQHJX-NPNXCVMYSA-N

说明

General description

5-PAHSA-d9 or 5-[((13,13,14,14,15,15,16,16,16-d9)palmitoyl)hydroxy]-stearic acid is a deuterated palmitoyl hydroxy-stearic acid wherein the nine protons of palmitoyl are replaced by deuterium. Palmitic acid-5-hydroxy-stearic acid (5-PAHSA) is the most downregulated fatty acid ester of hydroxy fatty acids (FAHFA) found in adipose tissues and in the serum of insulin-resistant mice.

PAHSA levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through GPR120 to enhance insulin-stimulated glucose uptake. Thus, FAHFAs are endogenous lipids with the potential to treat type 2 diabetes. Avanti has obtained a license from the patent holder to manufacture these products for research use.

Packaging

5 mL Clear Glass Sealed Ampule (860410C-1mg)

5 mL Clear Glass Sealed Ampule (860410C-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H302,H315,H319,H331,H336,H351,H361d,H372

pcodes

P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c