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关于此项目
经验公式（希尔记法）:
C41H79NO2
化学文摘社编号:
分子量:
618.07
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
N-C24:1-desoxymethylsphingosine, Avanti Research™ - A Croda Brand 860468P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860468P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860468P
lipid type
bioactive lipids
sphingolipids
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
Deoxydihydro ceramide (deoxyDHCer), nervonoyl (C24:1) is present in the mammals along with palmitoyl (C16) dihydroceramide. In general, deoxyDHCer modulates the cellular membrane properties and may contribute to its biological functionality.
General description
Ceramides are generated by the acylation of the sphingoid bases, sphingosine.
Packaging
5 mL Amber Glass Screw Cap Vial (860468P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
新产品
此项目有
Sphingolipid biosynthesis in man and microbes
Harrison PJ, et al.
Natural Product Reports, 35(9), 921-954 (2018)
Biophysical properties of novel 1-deoxy-(dihydro) ceramides occurring in mammalian cells
Jimenez-Rojo N, et al.
Biophysical Journal, 107(12), 2850-2859 (2014)
Junliang Wan et al.
Journal of agricultural and food chemistry, 67(46), 12953-12961 (2019-10-23)
Most common sphingolipids are comprised of "typical" sphingoid bases (sphinganine, sphingosine, and structurally related compounds) and are produced via the condensation of l-serine with a fatty acyl-CoA by serine palmitoyltransferase. Some organisms, including mammals, also produce "atypical" sphingoid bases that
Sarah T Pruett et al.
Journal of lipid research, 49(8), 1621-1639 (2008-05-24)
"Sphingosin" was first described by J. L. W. Thudichum in 1884 and structurally characterized as 2S,3R,4E-2-aminooctadec-4-ene-1,3-diol in 1947 by Herb Carter, who also proposed the designation of "lipides derived from sphingosine as sphingolipides." This category of amino alcohols is now
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