860495P
Avanti
Monomethyl Sphingosine (d18:1)
Avanti Research™ - A Croda Brand
别名:
N-methyl-D-erythro-sphingosine
产品名称
Monomethyl Sphingosine (d18:1), Avanti Research™ - A Croda Brand 860495P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 5 mg (860495P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 860495P
脂质类型
deuterated lipids
sphingolipids
运输
dry ice
储存温度
−20°C
SMILES字符串
OC[C@@](NC)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI key
LUMQNHNDMLZNDJ-OVMWUVNSSA-N
一般描述
Monomethyl sphingosine or N-methyl-D-erythro-sphingosine is a N-methyl derivative of sphingosine
应用
Monomethyl sphingosine or N-methyl-D-erythro-sphingosine may be used as one of the substrates for sphingosine methyltransferase to test its substrate specificity in rat kidney homogenate.
生化/生理作用
Monomethyl sphingosine inhibits protein kinase C. It also modulates other protein kinases and enzymes involved in signal transduction.
包装
5 mL Amber Glass Screw Cap Vial (860495P-5mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
Biological Function of Gangliosides (1994)
Handbook of Neurochemistry and Molecular Neurobiology:Neural Lipids (2009)
Santosh J Sacket et al.
Acta pharmacologica Sinica, 29(10), 1227-1232 (2008-09-27)
To characterize sphingosine methyltransferase in rat tissues. By using S-adenosyl-L-(methyl-3H) methionine, enzymatic activity was measured in the rat liver and kidney homogenates. The optimum pH and reaction time for the enzyme assay were pH 7.8 and 1 h. ZnCl2 inhibited
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