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经验公式（希尔记法）:
C28H55NO3
化学文摘社编号:
分子量:
453.74
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C10 Ceramide (d18:1/10:0), Avanti Research™ - A Croda Brand 860510P, powder
SMILES string
OC[C@]([H])(NC(CCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C28H55NO3/c1-3-5-7-9-11-12-13-14-15-16-18-19-21-23-27(31)26(25-30)29-28(32)24-22-20-17-10-8-6-4-2/h21,23,26-27,30-31H,3-20,22,24-25H2,1-2H3,(H,29,32)/b23-21+/t26-,27+/m0/s1
InChI key
FDWVAQFAMZLCAX-NBNLIBPQSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (860510P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860510P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
Application
C10 Ceramide (d18:1/10:0) or N-decanoyl-D-erythro-sphingosine has been used:
- as an internal standard in galactocerebrosidase (GALC) assay
- to study its role on the physical properties of edible organogels and on their ability to induce cell death of various cancer cell lines
- to study its mixing behavior with other ceramides having the same sphingosine base but varying N-linked acyl chain length
Biochem/physiol Actions
Ceramides modulate stress responses and inflammation. It also controls cell differentiation, proliferation and apoptosis.
General description
C10 Ceramide (d18:1/10:0) is a synthetic ceramide containing sphingosine with decanoic acid. It has a short acyl chain length than sphingosine acyl chain.
Packaging
5 mL Amber Glass Screw Cap Vial (860510P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Fernando Dupuy et al.
Chemistry and physics of lipids, 165(6), 615-629 (2012-07-12)
The organization of lipids within membranes strongly depends on the interaction with other lipid and protein molecules. Sphingolipids comprise a structurally diverse family, the ceramides being some of the simplest members. Although small chemical modifications of ceramide structure, such as
Michael A Rogers et al.
Food science & nutrition, 5(3), 579-587 (2017-06-03)
Short-chain ceramides, such as N-acetoyl-d-erythro-sphingosine (C2), have a remarkable ability to structure edible oils, such as canola oil, into self-standing organogels without any added saturated or trans fats. These short-chain ceramides are ubiquitously found in foods ranging from eggs to
Joseph J Orsini et al.
Clinical biochemistry, 42(9), 877-884 (2009-03-26)
The aim of this study was to develop a newborn screening algorithm for Krabbe disease. We measured the galactocerebrosidase activity of 139,074 anonymous newborns, 56 known carriers, and 16 Krabbe patients using a tandem mass spectrometry method. The activities were
Meenu N Perera et al.
Chemistry and physics of lipids, 194, 110-116 (2015-09-27)
A ceramide commonly found in mammalian cells, C16-ceramide (N-palmitoyl-d-erythro-sphingosine), is capable of forming large, protein-permeable channels in the mitochondrial outer membrane (MOM). However, C16-ceramide is unable to permeabilize the plasma membrane of erythrocytes. This specificity is unexpected considering that ceramide
Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
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