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经验公式（希尔记法）:
C42H81NO3
化学文摘社编号:
分子量:
648.10
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C24:1 神经酰胺 (d18:1/24:1 (15Z)), Avanti Research™ - A Croda Brand
packaging
pkg of 1 × 10 mg (860525P-10mg)
pkg of 1 × 25 mg (860525P-25mg)
pkg of 1 × 5 mg (860525P-5mg)
pkg of 1 × 50 mg (860525P-50mg)
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C42H81NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-42(46)43-40(39-44)41(45)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h17-18,35,37,40-41,44-45H,3-16,19-34,36,38-39H2,1-2H3,(H,43,46)/b18-17-,37-35+/t40-,41+/m0/s1
InChI key
VJSBNBBOSZJDKB-KPEYJIHVSA-N
assay
>99% (TLC)
form
powder
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
Application
C24:1 神经酰胺 (d18:1/24:1 (15Z)) 已被用作液相色谱-质谱仪的内部支架。 也适合在高效液相色谱/串联质谱法中作为标准品使用。
Biochem/physiol Actions
神经酰胺 (d18:1/24:1[15Z]) 水平在原发性开角型青光眼 (POAG) 中升高。它是人体动脉组织和血浆中主要不良心脑血管事件 (MACE) 的生物标志物。总之，神经酰胺是鞘磷脂途径中的第二信使，调节代谢疾病的病理生理学。
General description
神经酰胺包括含 C14 至 C24 饱和和单不饱和脂肪酸酰基链的刺状脂肪。它们存在于大多数哺乳动物组织中。
Packaging
5 mL 棕色玻璃螺旋盖小瓶 (860525P-10 mg)
5 mL 棕色玻璃螺旋盖小瓶 (860525P-5 mg)
5 mL 棕色玻璃螺旋盖小瓶 (860525P-50 mg)
5 mL 琥珀色玻璃螺旋盖小瓶 (860525P-25 mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Plasma ceramides as prognostic biomarkers and their arterial and myocardial tissue correlates in acute myocardial infarction
de Carvalho LP, et al.
JACC. Basic to translational science, 3(2), 163-175 (2018)
Human trabecular meshwork sphingolipid and ceramide profiles and potential latent fungal commensalism
Aljohani AJ, et al.
Investigative Ophthalmology & Visual Science, 55(6), 3413-3422 (2014)
Hypothalamic AMPK-ER stress-JNK1 axis mediates the central actions of thyroid hormones on energy balance
Martinez-Sanchez N, et al.
Cell Metabolism, 26(1), 212-229 (2017)
Increased ceramide content and NFkappaB signaling may contribute to the attenuation of anabolic signaling after resistance exercise in aged males
Rivas DA, et al.
Journal of Applied Physiology, 113(11), 1727-1736 (2012)
Atypical surface behavior of ceramides with nonhydroxy and 2-hydroxy very long-chain (C28-C32) PUFAs
Penalva DA, et al.
Biochimica et Biophysica Acta - Biomembranes, 1838(3), 731-738 (2014)
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