860543P
Avanti
C12 Glucosyl(β) Ceramide (d18:1/12:0)
Avanti Research™ - A Croda Brand
别名:
D-glucosyl-β-1,1′-N-lauroyl-D-erythro-sphingosine
Product Name
C12 Glucosyl(β) Ceramide (d18:1/12:0), Avanti Research™ - A Croda Brand 860543P, powder
表单
powder
包装
pkg of 1 × 5 mg (860543P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 860543P
脂质类型
sphingolipids
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O
InChI
1S/C36H69NO8/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-30(39)29(28-44-36-35(43)34(42)33(41)31(27-38)45-36)37-32(40)26-24-22-20-17-12-10-8-6-4-2/h23,25,29-31,33-36,38-39,41-43H,3-22,24,26-28H2,1-2H3,(H,37,40)/b25-23+/t29-,30+,31?,33+,34?,35?,36+/m0/s1
InChI key
IYCYEZLMOLRFAN-QGJHTTTBSA-N
应用
C12 Glucosyl(β) Ceramide (d18:1/12:0) or D-glucosyl-β-1,1′-N-lauroyl-D-erythro-sphingosine has been used in lipid binding assay to assess the binding of monoclonal antibodies (mAbs). It may be used as an internal standard to spike cell lysate and to quantify lipid species using fourier transform mass spectrometry (FTMS) analysis. It may also be used as an internal standard for lipid extraction in U87MG (human glioma cell line).
包装
5 mL Amber Glass Screw Cap Vial (860543P-5mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
法规信息
涉药品监管产品
Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
Hernandez-Tiedra S, et al.
Autophagy, 12(11), 2213-2229 (2016)
Shelly J Krebs et al.
Immunity, 50(3), 677-691 (2019-03-17)
Lineage-based vaccine design is an attractive approach for eliciting broadly neutralizing antibodies (bNAbs) against HIV-1. However, most bNAb lineages studied to date have features indicative of unusual recombination and/or development. From an individual in the prospective RV217 cohort, we identified
David B Iaea et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(4), 158609-158609 (2020-01-10)
STARD4, a member of the evolutionarily conserved START gene family, is a soluble sterol transport protein implicated in cholesterol sensing and maintenance of cellular homeostasis. STARD4 is widely expressed and has been shown to transfer sterol between liposomes as well
Sonia Hernández-Tiedra et al.
Autophagy, 12(11), 2213-2229 (2016-11-02)
Autophagy is considered primarily a cell survival process, although it can also lead to cell death. However, the factors that dictate the shift between these 2 opposite outcomes remain largely unknown. In this work, we used Δ9-tetrahydrocannabinol (THC, the main
MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes.
Christophe A C Freyre et al.
Molecular cell, 76(5), 811-825 (2019-10-20)
Physical contact between organelles is vital to the function of eukaryotic cells. Lipid droplets (LDs) are dynamic organelles specialized in lipid storage that interact physically with mitochondria in several cell types. The mechanisms coupling these organelles are, however, poorly understood
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