Name: C24:1 Glucosyl(β) Ceramide (d18:1/24:1(15Z))
Brand: AVANTI

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About This Item

经验公式（希尔记法）:

C₄₈H₉₁NO₈

CAS Number:

887907-50-8

分子量:

810.24

MDL编号:

MFCD22416611

UNSPSC代码:

12352211

NACRES:

NA.25

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Product Name

C24:1 Glucosyl(β) Ceramide (d18:1/24:1(15Z)), Avanti Research^™ - A Croda Brand 860549P, powder

表单

powder

包装

pkg of 1 × 5 mg (860549P-5mg)

制造商/商品名称

Avanti Research^™ - A Croda Brand 860549P

脂质类型

sphingolipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O

InChI

1S/C48H91NO8/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-44(52)49-41(40-56-48-47(55)46(54)45(53)43(39-50)57-48)42(51)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h17-18,35,37,41-43,45-48,50-51,53-55H,3-16,19-34,36,38-40H2,1-2H3,(H,49,52)/

InChI key

WBOZIXHPUPAOIA-JZZPSRGZSA-N

一般描述

β-Glucosylceramides or glucocerebrosides (GlcCers) are synthesized from the glycosphingolipids by β-GlcCer synthase. They are synthesized in Golgi and endoplasmic reticulum and localized in the cytosolic side of cell membrane. GlcCers are omnipresent.

应用

C24:1 Glucosyl(β) Ceramide (d18:1/24:1(15Z)) may be used:

as a standard hexosylceramide for hydrophilic interaction chromatography-based liquid chromatography mass spectroscopy
to test its nuclear factor of activated T-cells (NFAT) activation
in human natural killer T (NKT) cell potency assays

生化/生理作用

β-Glucosylceramides (β-GlcCer) levels are elevated inlevels in Gaucher′s disease, due to the deficiency of β-glucosidase. β-GlcCer participates in the inflammatory and acquired immune responses by binding mincle on myeloid cells and has immunostimulatory activity.

包装

5 mL Amber Glass Screw Cap Vial (860549P-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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