860550P
Avanti
Biotin Sphingosine
Avanti Research™ - A Croda Brand
别名:
omega-biotinyl D-erythro-sphingosine
产品名称
Biotin Sphingosine, Avanti Research™ - A Croda Brand 860550P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (860550P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 860550P
脂质类型
sphingolipids
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@]1(CCCCC(NCCCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@](N)([H])CO)=O)SC[C@@]2([H])[C@]1([H])NC(N2)=O
InChI
1S/C28H52N4O4S/c29-22(20-33)24(34)16-12-10-8-6-4-2-1-3-5-7-9-11-15-19-30-26(35)18-14-13-17-25-27-23(21-37-25)31-28(36)32-27/h12,16,22-25,27,33-34H,1-11,13-15,17-21,29H2,(H,30,35)(H2,31,32,36)/b16-12+/t22-,23-,24+,25-,27-/m0/s1
InChI key
NYQVYZZGZCNEMF-RPRIXWAOSA-N
一般描述
Biotin Sphingosine is a derivative of sphingosine. It contains a biotin moiety linked to the ω-terminal of its fatty-acid chain.
应用
Biotin Sphingosine has been used as a substrate in sphingosine kinases (SphK) assay. It has also been used to label wt- ceramide synthase 1 (CerS1) expressed in UM-SCC-22A cells, to study the interaction between CerS1-generated C18-ceramide and light chain 3 β (LC3B).
生化/生理作用
Biotin Sphingosineplays a vital role in identifying sphingosine interaction with acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A).
包装
5 mL Amber Glass Screw Cap Vial (860550P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
法规信息
新产品
此项目有
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
Sentelle R, et al.
Nature Chemical Biology, 8(10), 831-831 (2012)
Bioactive Sphingolipids in Cancer Biology and Therapy (2015)
An assay for sphingosine kinase activity using biotinylated sphingosine and streptavidin-coated membranes
Roberts J, et al.
Analytical biochemistry, 331(1), 122-129 (2004)
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