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Merck
CN

860578P

Avanti

C24 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/24:0)

Avanti Research™ - A Croda Brand

别名:

3-O-sulfo-D-galactosyl-β1-1′-N-lignoceroyl-D-erythro-sphingosine (ammonium salt), (synthetic)

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关于此项目

经验公式（希尔记法）:
C48H96N2O11S
化学文摘社编号:
1246304-32-4
分子量:
909.35
UNSPSC Code:
12352211
NACRES:
NA.25

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产品名称

C24 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/24:0), Avanti Research™ - A Croda Brand 860578P, powder

InChI

1S/C48H93NO11S.H3N/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-44(52)49-41(42(51)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2)40-58-48-46(54)47(60-61(55,56)57)45(53)43(39-50)59-48;/h35,37,41-43,45-48,50-51,53-54H,3-34,36,38-40H2,1-2H3,(H,

InChI key

DVNDZUUWWJPMSI-RYBIKTNWSA-N

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H]([C@H]1CO)O.[NH4+]

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860578P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860578P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

Biochem/physiol Actions

Sulfatide regulates the biological functions of microbial infection, hemostasis, nervous system and immune system. Accumulation of lysosomal sulfatide leads to metachromatic leukodystrophy (MLD). Sulfatide modulates protein trafficking, signal transduction and neuronal cell differentiation.

General description

3-O-sulfogalactosylceramide, also called as sulfatide, is a sulfoglycolipid produced by ceramide galactosyltransferase and cerebroside sulfotransferase. It was first extracted from the human brain. Sulfatide is found majorly in the cellular membrane, Golgi apparatus and lysosomes.

Packaging

5 mL Amber Glass Screw Cap Vial (860578P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

法规信息

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分析证书(COA)

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Medical Applications of Mass Spectrometry (2011)
Medical Applications of Mass Spectrometry (2011)
Tadanobu Takahashi et al.
Journal of lipid research, 53(8), 1437-1450 (2012-05-24)
Sulfatide is 3-O-sulfogalactosylceramide that is synthesized by two transferases (ceramide galactosyltransferase and cerebroside sulfotransferase) from ceramide and is specifically degraded by a sulfatase (arylsulfatase A). Sulfatide is a multifunctional molecule for various biological fields including the nervous system, insulin secretion

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