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Merck
CN

860597P

Avanti

C24:1 Lactosyl(β) Ceramide (d18:1/24:1)

Avanti Research™ - A Croda Brand

别名:

D-lactosyl-β1-1′-N-nervonoyl-D-erythro-sphingosine

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关于此项目

经验公式（希尔记法）:
C54H101NO13
化学文摘社编号:
483370-78-1
分子量:
972.38
MDL编号:
MFCD22416892
UNSPSC代码:
12352211
NACRES:
NA.25

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产品名称

C24:1 Lactosyl(β) Ceramide (d18:1/24:1), Avanti Research™ - A Croda Brand 860597P, powder

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 5 mg (860597P-5mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 860597P

脂质类型

sphingolipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O

InChI

1S/C54H101NO13/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-46(59)55-42(43(58)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2)41-65-53-51(64)49(62)52(45(40-57)67-53)68-54-50(63)48(61)47(60)44(39-56)66-54/h17-18,35,37,42-45,47-54,56-58,60-64H,

InChI key

MKOKWBRPIBQYJJ-WZBOJYASSA-N

相关类别

一般描述

Lactosylceramide (LacCer) is a glycosphingolipid, which has a hydrophobic ceramide lipid and a hydrophilic sugar moiety. It is present mainly in the nervous system and myelin sheath.

生化/生理作用

Lactosylceramide (LacCer) is a structural and signaling lipid. It aids microbial attachment and also functions as an adhesion receptor for pathogens. LacCer is essential for signal transduction and cell adhesion. It controls cell proliferation and apoptosis. LacCer is implicated in cellular stress response and microbial pathogenesis. It facilitates innate immune responses and host-tissue pathogen interactions.

包装

5 mL Amber Glass Screw Cap Vial (860597P-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharide, 191, 106-114 (2009)
Daniela Couto et al.
Chemistry and physics of lipids, 191, 106-114 (2015-09-01)
Galactosylceramide (GalCer) and lactosylceramide (LacCer) are structural and signaling lipids, playing important roles in signal transduction and cell adhesion. They are especially abundant in the nervous system and in important components of the myelin sheath. Although neurodegenerative disorders are associated
Jarod A Fincher et al.
Scientific reports, 9(1), 17508-17508 (2019-11-27)
Neutral lipids have been implicated in a host of potentially debilitating human diseases, such as heart disease, type-2 diabetes, and metabolic syndrome. Matrix-assisted laser desorption ionization (MALDI), the method-of-choice for mass spectrometry imaging (MSI), has led to remarkable success in

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