产品名称
C18:1 Ceramide-1-Phosphate (d18:1/18:1(9Z)), Avanti Research™ - A Croda Brand 860599C
InChI key
OLFFCEGYMCQDKZ-CFRDMXQMSA-N
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC/C=C\CCCCCCCC)=O)COP([O-])(O)=O.[NH4+]
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (860599C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860599C
concentration
1 mg/mL (860599C-1mg)
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
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General description
Ceramide-1-phosphate (C1P) is a ceramide-derived metabolite, which belongs to the class of bioactive lipid mediators.
Application
C18:1 Ceramide-1-Phosphate (d18:1/18:1(9Z)) may be used for fluorescence analysis of phosphatidic acid-binding tetravalent peptide (PAB-TP) phospholipid specificity. It may also be used in liposome cosedimentation assay to compare its affinity with α-synuclein-N.
Biochem/physiol Actions
Ceramide-1-phosphate (C1P) regulates cell survival, cell growth and death. It mediates inflammatory response and phagocytosis.
Packaging
5 mL Clear Glass Sealed Ampule (860599C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
wgk
WGK 3
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
危险化学品
易制毒化学品（2类）
此项目有
Characterization of alpha-synuclein N-terminal domain as a novel cellular phosphatidic acid sensor
Yamada H, et al.
FEBS Journal (2019)
Development of a novel tetravalent synthetic peptide that binds to phosphatidic acid
Ogawa R, et al.
PLoS ONE, 10(7) (2015)
Development of a novel tetravalent synthetic peptide that binds to phosphatidic acid
Ogawa R, et al.
Testing, 10(7) (2015)
Characterization of alpha-synuclein N-terminal domain as a novel cellular phosphatidic acid sensor
Yamada H, et al.
The FEBS journal (2019)
Blood sphingolipidomics in healthy humans: impact of sample collection methodology
Hammad SM, et al.
Journal of Lipid Research, 51(10), 3074-3087 (2010)
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