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关于此项目
经验公式(希尔记法):
C26H53NO3
化学文摘社编号:
分子量:
427.70
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C8 Dihydroceramide (d18:0/8:0), Avanti Research™ - A Croda Brand 860626P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (860626P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860626P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC
InChI
1S/C26H53NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h24-25,28-29H,3-23H2,1-2H3,(H,27,30)/t24-,25+/m0/s1
InChI key
LGOFBZUQIUVJFS-LOSJGSFVSA-N
Application
C8 Dihydroceramide (d18:0/8:0) has been used as an internal standard to quantify the lipid extracted from human plasma by liquid chromatography mass spectrometry during high-throughput plasma lipidomics.
Biochem/physiol Actions
C8 Dihydroceramide (d18:0/8:0) or N-octanoyl-D-erythro-sphinganine, is a synthetic dihydroceramide. Dihydroceramide acts as a precursor for de-novo ceramide synthesis. C8 Dihydroceramide mimics γ-tocotrienol (γTE) in stimulating NF-κB-target protein A20 expression, increasing endoplasmic reticulum (ER) stress and reducing tumor necrosis factor (TNF)-triggered nuclear factor kappa B (NF-κB) activation.
Packaging
5 mL Amber Glass Screw Cap Vial (860626P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3