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经验公式（希尔记法）:
C30H61NO3
化学文摘社编号:
分子量:
483.81
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C12 Dihydroceramide (d18:0/12:0), Avanti Research™ - A Croda Brand 860635P, powder
InChI
1S/C30H61NO3/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-29(33)28(27-32)31-30(34)26-24-22-20-17-12-10-8-6-4-2/h28-29,32-33H,3-27H2,1-2H3,(H,31,34)/t28-,29+/m0/s1
InChI key
UHWYQXNZIBLESO-URLMMPGGSA-N
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (860635P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860635P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
Application
C12 Dihydroceramide has been used as an internal standard for quantification of dihydroceramides in adipose tissue by liquid chromatography - tandem mass spectrometry (LC-MS-MS).
Packaging
5 mL Amber Glass Screw Cap Vial (860635P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue
Mcilroy GD, et al.
Biochemical Pharmacology, 100, 86-97 (2016)
George D Mcilroy et al.
Biochemical pharmacology, 100, 86-97 (2015-11-26)
Fenretinide (FEN) is a synthetic retinoid that inhibits obesity and insulin resistance in high-fat diet (HFD)-fed mice and completely prevents 3T3-L1 pre-adipocyte differentiation. The aim of this study was to determine the mechanism(s) of FEN action in 3T3-L1 adipocytes and
Gergely Karsai et al.
The Journal of biological chemistry, 295(7), 1889-1897 (2019-12-22)
Sphingolipids (SLs) are structurally diverse lipids that are defined by the presence of a long-chain base (LCB) backbone. Typically, LCBs contain a single Δ4E double bond (DB) (mostly d18:1), whereas the dienic LCB sphingadienine (d18:2) contains a second DB at
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