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经验公式(希尔记法):
C24H42D5NO7
化学文摘社编号:
分子量:
466.66
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Assay:
>99% (TLC)
Form:
powder
产品名称
葡糖基(β) 鞘氨醇-d5, Avanti Research™ - A Croda Brand
InChI
1S/C24H47NO7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(27)18(25)17-31-24-23(30)22(29)21(28)20(16-26)32-24/h14-15,18-24,26-30H,2-13,16-17,25H2,1H3/b15-14+/t18-,19+,20+,21+,22-,23+,24+/m0/s1/i1D3,2D2
InChI key
HHJTWTPUPVQKNA-JCMYXXMQSA-N
SMILES string
[H][C@](/C=C/CCCCCCCCCCCC([2H])(C([2H])([2H])[2H])[2H])(O)[C@](N)([H])CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860636P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
Application
葡萄糖基(β)鞘氨醇-d5已用作内标,用于通过液相色谱-串联质谱法定量各种样品中的溶血己糖基神经酰胺。
Biochem/physiol Actions
葡萄糖基鞘氨醇具有调节脑微粒体中Ca2+释放的能力。它作为戈谢病(GD)的潜在生物标记物。
Packaging
5 mL棕色玻璃螺旋盖小瓶(860636P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
法规信息
美国出口管控产品
此项目有
Glucosylsphingosine is a highly sensitive and specific biomarker for primary diagnostic and follow-up monitoring in Gaucher disease in a non-Jewish, Caucasian cohort of Gaucher disease patients
Rolfs A, et al.
PLoS ONE, 8(11) (2013)
LC-MS/MS multiplex analysis of lysosphingolipids in plasma and amniotic fluid: a novel tool for the screening of sphingolipidoses and Niemann-Pick type C disease
Pettazzoni M, et al.
PLoS ONE, 12(7) (2017)
LC-MS/MS multiplex analysis of lysosphingolipids in plasma and amniotic fluid: a novel tool for the screening of sphingolipidoses and Niemann-Pick type C disease
Pettazzoni M, et al.
Testing, 12(7) (2017)
Mercedes Roca-Espiau et al.
Journal of orthopaedic surgery and research, 14(1), 383-383 (2019-11-23)
Chronic fatigue (CFg) is a prevalent symptom in Gaucher disease (GD) at diagnosis (79%) and remains in a quarter of patients after years of therapy. Bone abnormalities are present in over 70% and peripheral neuropathy in about 11% of the
Muscle-tendon weakness contributes to chronic fatigue syndrome in Gaucher?s disease
Roca-Espiau M, et al.
Journal of Orthopaedic Surgery and Research, 14(1), 383-383 (2019)
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