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Merck
CN

860639P

Avanti

Lyso SM-d7

Avanti Research - A Croda Brand

别名:

sphingosylphosphorylcholine-d7

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关于此项目

经验公式(希尔记法):
C23H42D7N2O5P
化学文摘社编号:
分子量:
471.66
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Assay:
>99% (TLC)
Form:
powder
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产品名称

Lyso SM-d7, Avanti Research - A Croda Brand 860639P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860639P-1mg), pkg of 1 × 5 mg (860639P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860639P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])(O)[C@@]([H])(N)COP([O-])(OCC[N+](C)(C)C)=O

InChI key

JLVSPVFPBBFMBE-SPXZQVPJSA-N

General description

Lyso-sphingomyelin (Lyso SM)- d7, is a deuterated derivative of Lyso SM. Lyso SM is an amphiphilic lysophospholipid containing sphingoid backbone and a phosphorylcholine. It is a de-acylated form of sphingomyelin.
Sphingosylphosphorylcholine is derived from sphingomyelin. It is known to be localized to plasma and also present in lipoproteins.

Biochem/physiol Actions

Lyso-sphingomyelin (Lyso SM) or sphingosylphosphorylcholine (SPC) serves as a multifunctional bioactive sphingolipid in cardiovascular system, immune system, central nervous system and skin. It has a potential to regulate cell proliferation, migration, differentiation, metabolism and apoptosis. Patients with pathological conditions such as atopic dermatitis, Niemann-Pick disease (NPD) and cancer show considerably higher levels of Lyso SM.
Lysosphingolipids serves as a marker for many sphingolipidoses. Sphingosylphosphorylcholine serves as a bioactive lipid in some tissues and immune system.

Packaging

5 mL Amber Glass Screw Cap Vial (860639P-1mg)
5 mL Amber Glass Screw Cap Vial (860639P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


存储类别

11 - Combustible Solids

flash_point_f

No data available

flash_point_c

No data available



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