860649P
Avanti
C24 Ceramide (d17:1/24:0)
Avanti Research™ - A Croda Brand
别名:
N-lignoceroyl-D-erythro-sphingosine (C17 base)
Product Name
C24 Ceramide (d17:1/24:0), Avanti Research™ - A Croda Brand 860649P, powder
表单
powder
包装
pkg of 1 × 10 mg (860649P-10mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 860649P
脂质类型
sphingolipids
运输
dry ice
储存温度
−20°C
SMILES字符串
OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCC
InChI
1S/C41H81NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-25-27-29-31-33-35-37-41(45)42-39(38-43)40(44)36-34-32-30-28-26-16-14-12-10-8-6-4-2/h34,36,39-40,43-44H,3-33,35,37-38H2,1-2H3,(H,42,45)/b36-34+/t39-,40+/m0/s1
InChI key
OWQPALVMZWREMV-PUYNVXOJSA-N
一般描述
C24 Ceramide (d17:1/24:0) is a synthetic ceramide derived from a C17 sphingosine with lignoceric acid. Ceramide synthase 2 is responsible for the synthesis of C24 ceramide.
应用
C24 Ceramide (d17:1/24:0) has been used as an internal standard to quantify ceramide content in both subcutaneous and visceral adipose tissue by ultraperformance liquid chromatography - tandem mass spectrometery (UPLC-MS/MS).
生化/生理作用
C24 Ceramide (d17:1/24:0) plays a vital role in inducing cell death. Altered levels of C24 Ceramide might be a potential indication in tumor monitoring.
包装
5 mL Amber Glass Screw Cap Vial (860649P-10mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Agnieszka U Blachnio-Zabielska et al.
International journal of molecular sciences, 19(12) (2018-12-14)
Ceramide accumulation in muscle and in liver is implicated in the induction of insulin resistance. Much less in known about the role of ceramide in adipose tissue. The aim of the present study was to elucidate the role of ceramide
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain
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