产品名称
C24:1 Ceramide (d17:1/24:1(15Z)), Avanti Research™ - A Croda Brand 860650P, powder
InChI
1S/C41H79NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-25-27-29-31-33-35-37-41(45)42-39(38-43)40(44)36-34-32-30-28-26-16-14-12-10-8-6-4-2/h17-18,34,36,39-40,43-44H,3-16,19-33,35,37-38H2,1-2H3,(H,42,45)/b18-17-,36-34+/t39-,40+/m0/s1
InChI key
YTXGSYSKVFVWFG-AHTJCSRDSA-N
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCC
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860650P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860650P
lipid type
sphingolipids
deuterated lipids
shipped in
dry ice
storage temp.
−20°C
Application
C24:1 Ceramide (d17:1/24:1(15Z)) has been used as an internal standard to measure ceramide content in the tissue samples by mass spectrometery.
Biochem/physiol Actions
Ceramides play an important role in cell signaling, cell differentiation, proliferation and apoptosis.
General description
C24:1 Ceramide (d17:1/24:1(15Z)) is a synthetic ceramide derived from a C17 sphingosine with nervonic acid (a monounsaturated analog of lignoceric acid (24:0)).
Packaging
5 mL Amber Glass Screw Cap Vial (860650P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Long-term follow-up of muscle lipid accumulation, mitochondrial activity and oxidative stress and their relationship with impaired glucose homeostasis in high fat high fructose diet-fed rats
Wang Y, et al.
The Journal of Nutritional Biochemistry, 64, 182-197 (2019)
Agnieszka U Blachnio-Zabielska et al.
International journal of molecular sciences, 19(12) (2018-12-14)
Ceramide accumulation in muscle and in liver is implicated in the induction of insulin resistance. Much less in known about the role of ceramide in adipose tissue. The aim of the present study was to elucidate the role of ceramide
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain
Ling Chen et al.
Oncology reports, 34(1), 447-454 (2015-05-16)
Endocannabinoids and ceramides have demonstrated growth inhibition, cell death induction and pro-apoptotic activity in cancer research. In the present study, we describe the profiles of two major endocannabinoids, ceramides, free fatty acids and relevant metabolic enzymes in 47 pairs of
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