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经验公式（希尔记法）:
C36H60D7NO17
化学文摘社编号:
分子量:
792.96
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.12
Assay:
99% (TLC)
Form:
powder
产品名称
Lyso GB3-d7 (synthetic), powder
InChI key
GRGNVOCPFLXGDQ-IZKFDWHNSA-N
SMILES string
O[C@H]1[C@H](OC[C@H](N)[C@H](O)/C=C/CCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O)[C@H]2O)O[C@H]3O[C@H](CO)[C@@H]([C@H](O)[C@H]3O)O)[C@@H]1O
assay
99% (TLC)
form
powder
packaging
package of 1 × 100 μg (860682P-100UG)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
Globotriaosylsphingosine-d7 (Lyso GB3-d7) is a deuterated derivative of globotriaosylsphingosine (Lyso-GB3). Lyso GB3 is a bioactive glycolipid circulating in the blood. It is a deacylated form of globotriaosylceramide.
Biochem/physiol Actions
Globotriaosylsphingosine (Lyso GB3) accumulates to a greater extent in fabry disease.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (860682P-100UG)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
The Fabry disease-associated lipid Lyso-Gb3 enhances voltage-gated calcium currents in sensory neurons and causes pain
Choi L, et al.
Neuroscience Letters, 594, 163-168 (2015)
Lyso-Gb3 activates Notch1 in human podocytes
Sanchez N, et al.
Human Molecular Genetics, 24(20), 5720-5732 (2015)
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