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经验公式(希尔记法):
C23H40D9N2O5P
化学文摘社编号:
分子量:
473.67
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.12
Assay:
99% (TLC)
Form:
powder
产品名称
Lyso-SM-d9, powder, Avanti Research™ - A Croda Brand (860685P)
InChI
1S/C23H49N2O5P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)22(24)21-30-31(27,28)29-20-19-25(2,3)4/h17-18,22-23,26H,5-16,19-21,24H2,1-4H3/b18-17+/t22-,23+/m0/s1/i2D3,3D3,4D3
InChI key
JLVSPVFPBBFMBE-IQSZTMPESA-N
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(N)COP([O-])(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O
assay
99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860685P-1MG)
manufacturer/tradename
Avanti Research™ - A Croda Brand (860685P)
shipped in
dry ice
storage temp.
−20°C
General description
Lyso-SM-d9 is a deuterated lyso-SM. Lyso sphingomyelin (Lyso-SM) is obtained from sphingomyelin due to the cleavage of N-acyl linkage of ceramides in sphingomyelin by the help of hydrolase.
Biochem/physiol Actions
Lyso sphingomyelin (Lyso-SM) functions as lipid mediators. It plays a vital role in cellular functioning of the skin, blood vessels, brain and heart. It also helps in the functioning of the immune system.
Packaging
5 mL Amber Glass Screw Cap Vial
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Lyso-sphingomyelin is elevated in dried blood spots of Niemann-Pick B patients
Chuang W L, et al.
Molecular Genetics and Metabolism, 111(2), 209-211 (2014)
A novel enzyme that cleaves the N-acyl linkage of ceramides in various glycosphingolipids as well as sphingomyelin to produce their lyso forms.
Ito M
The Journal of Biological Chemistry, 270(41), 24370-24374 (1995)
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