产品名称
16:0 DBCO PE, Avanti Research™ - A Croda Brand 870128P, powder
InChI key
VMNQBMCGXSXSJG-GLOFXQGCSA-N
SMILES string
[H][C@@](COP([O-])(OCCNC(CCC(N1CC(C=CC=C2)=C2C#CC3=C1C=CC=C3)=O)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (870128P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 870128P
shipped in
dry ice
storage temp.
−20°C
General description
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyl (16:0 DBCO PE) is a head group modified lipid containing dibenzocyclooctyne (DBCO). It is a widely used reagent in click chemistry.
Application
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyl (16:0 DBCO PE or DPPE-DBCO) has been used in preparation of DBCO-presenting lipid bilayers. It has also been used in preparation of clickable cubosomes for antibody-free drug targeting and imaging applications.
Packaging
5 mL Amber Glass Screw Cap Vial (870128P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
flash_point_f
No data available
flash_point_c
No data available
Nicolas Alcaraz et al.
Bioconjugate chemistry, 29(1), 149-157 (2017-11-29)
The combination of copper-free click chemistry with metabolic labeling offers new opportunities in drug delivery. The objective of this study was to determine whether cubosomes functionalized with azide or dibenzocyclooctyne (DBCO) groups are able to undergo copper-free click chemistry with
Simon Finn Mayer et al.
Biochimica et biophysica acta. Biomembranes, 1861(10), 183023-183023 (2019-07-22)
Pore-forming antimicrobial peptides (AMPs) are attracting interest as cytolytic antibiotics and drug delivery agents with potential use for targeting cancer cells or multidrug-resistant pathogens. Ceratotoxin A (CtxA) is an insect-derived cytolytic AMP with 36 amino acids that is thought to
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