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Merck
CN

870202O

Avanti

18:1 PDP PE

Avanti Research™ - A Croda Brand

别名:

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate] (sodium salt)

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关于此项目

经验公式（希尔记法）:
C49H84N2O9PNaS2
CAS Number:
474944-13-3
分子量:
963.29
MDL编号:
MFCD22495340
UNSPSC代码:
12352211
NACRES:
NA.25

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Product Name

18:1 PDP PE, Avanti Research™ - A Croda Brand 870202O

表单

liquid

包装

pkg of 1 × 25 mg (870202O-25mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 870202O

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCCNC(CCSSC1=CC=CC=N1)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C49H85N2O9PS2.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-36-48(53)57-43-45(60-49(54)37-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)44-59-61(55,56)58-41-40-50-46(52)38-42-62-63-47-35-33-34-39-51-47;/h17-20,33-35,39,45H,3-16,21-32,36-38,40-44H2,1-2H3,(H,50,52)(H,55,56);/q;+1/p-1/b19-17-,20-18-;/t45-;/m1./s1

InChI key

LFMWVVNPVNIPJG-JQRYTBKHSA-M

相关类别

一般描述

18:1 PDP PE, also referred as 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate], is a head group modified functionalized lipid. Functionalized lipids mainly act as reporter molecules.

应用

18:1 PDP PE may be used in the preparation of hydrophobized disulfide-linked oligodeoxyribonucleotide (ODN). It may also be used in the preparation of liposomes.

包装

5 mL Clear Glass Sealed Ampule (870202O-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

10 - Combustible liquids

WGK

WGK 3

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Pathways for modulating exosome lipids identified by high-density lipoprotein-like nanoparticle binding to scavenger receptor type B-1
Angeloni NL, et al.
Scientific reports, 6(1) (2016)
Disulfide-linked liposomes: effective delivery vehicle for Bcl-2 antisense oligodeoxyribonucleotide G3139
Weecharangsan W, et al.
Anticancer Research, 30(1), 31-37 (2010)
Hitchhiking nanoparticles: Reversible coupling of lipid-based nanoparticles to cytotoxic T lymphocytes
Wayteck L, et al.
Biomaterials, 77, 243-254 (2016)
Laura Wayteck et al.
Biomaterials, 77, 243-254 (2015-11-26)
Following intravenous injection of anti-cancer nanomedicines, many barriers need to be overcome en route to the tumor. Cell-mediated delivery of nanoparticles (NPs) is promising in terms of overcoming several of these barriers based on the tumoritropic migratory properties of particular
Wanlop Weecharangsan et al.
Anticancer research, 30(1), 31-37 (2010-02-13)
Disulfide-linked oligodeoxyribonucleotide (ODN) liposomes were formulated and evaluated for the delivery of antisense ODN G3139 in KB human oral carcinoma cells. Liposomes composed of 1,2-di-(9Z-octadecenoyl)-3-trimethylammo-nium-propane (DOTAP)/egg phosphatidylcholine/alpha-tocopheryl polyethylene glycol 1000 succinate were incorporated with hydrophobized disulfide-linked ODN. Disulfide-linked ODN liposomes
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