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经验公式（希尔记法）:
C41H77NO11PNa
化学文摘社编号:
分子量:
814.01
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
16:0 Succinyl PE, Avanti Research™ - A Croda Brand 870225P, powder
SMILES string
[H][C@@](COP([O-])(OCCN([H])C(CCC(O)=O)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
InChI
1S/C41H78NO11P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-40(46)50-35-37(36-52-54(48,49)51-34-33-42-38(43)31-32-39(44)45)53-41(47)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h37H,3-36H2,1-2H3,(H,42,43)(H,44,45)(H,48,49);/q;+1/p-1/t37-;/m1./s1
InChI key
CSBBOJBLMMDIFP-GKEJWYBXSA-M
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (870225P-25mg)
pkg of 1 × 500 mg (870225P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 870225P
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl) (DPPE) is used in production of PHEA-EDA-DPPE-GAL copolymer. This copolymer is used in preparation of ribavirin (RBV) tripalmitate-loaded nanoparticles, that act as hepatic cell-targeted carriers for hepatitis C treatment.
General description
16:0 Succinyl PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)(DPPE), is a head group modified functionalized lipid. Functionalized lipids act as reporter molecules.
Packaging
20 mL Clear Glass Screw Cap Vial (870225P-500mg)
5 mL Amber Glass Screw Cap Vial (870225P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Emanuela Fabiola Craparo et al.
Journal of biomedical nanotechnology, 9(6), 1107-1122 (2013-07-19)
In this paper, we describe the preparation of liver-targeted nanoparticles potentially able to carry to hepatocytes a ribavirin (RBV) prodrug, exploiting the presence of carbohydrate receptors in the liver (i.e., ASGPR in hepatocytes). These particles were obtained starting from a
Mariusz Kepczynski et al.
Biochimica et biophysica acta, 1858(10), 2362-2379 (2016-03-08)
Synthetic lipids and surfactants that do not exist in biological systems have been used for the last few decades in both basic and applied science. The most notable applications for synthetic lipids and surfactants are drug delivery, gene transfection, as
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