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经验公式（希尔记法）:
C19H37NO2
化学文摘社编号:
分子量:
311.50
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C17:1 anandamide, Avanti Research™ - A Croda Brand 870431P, powder
InChI key
IGADVTJDHNVILM-FPLPWBNLSA-N
SMILES string
O=C(CCCCCCCC/C=C\CCCCCC)NCCO
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (870431P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 870431P
lipid type
bioactive lipids
shipped in
dry ice
storage temp.
−20°C
General description
C17:1 anandamide, also known as 10Z-heptadecenoylethanolamide, is a N-acyl ethanolamide derivative of heptadecanoic acid.
Application
C17:1 anandamide or 10Z-heptadecenoylethanolamide has been used as an internal standard in mass spectrometry analysis for the measurement of 2-arachidonoyl glycerol (2-AG) in brain tissue. It has also been used as a substrate for N-acylethanolamine acid amidase (NAAA) enzyme.
Packaging
5 mL Clear Glass Sealed Ampule (870431P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Yoki Nakamura et al.
eLife, 8 (2019-10-10)
Cocaine is an addictive drug that acts in brain reward areas. Recent evidence suggests that cocaine stimulates synthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG) in midbrain, increasing dopamine neuron activity via disinhibition. Although a mechanism for cocaine-stimulated 2-AG synthesis is known
Oscar Sasso et al.
Pain, 154(3), 350-360 (2012-12-12)
Fatty acid ethanolamides (FAEs), which include palmitoylethanolamide (PEA) and oleoylethanolamide (OEA), are endogenous agonists of peroxisome proliferator-activated receptor-α (PPAR-α) and important regulators of the inflammatory response. They are degraded in macrophages by the lysosomal cysteine amidase, N-acylethanolamine acid amidase (NAAA).
Natsuo Ueda et al.
Biochimica et biophysica acta, 1801(12), 1274-1285 (2010-08-26)
Ethanolamides of different long-chain fatty acids constitute a class of endogenous lipid molecules generally called N-acylethanolamines (NAEs). They contain N-arachidonoylethanolamine (anandamide), N-palmitoylethanolamine, and N-oleoylethanolamine, which receive considerable attention because of their actions as an endogenous cannabinoid receptor ligand (endocannabinoid), an
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