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安全信息

870520C

Avanti

18:1 CDP DG

Avanti Polar Lipids 870520C

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别名:
1,2-dioleoyl-sn-glycero-3-(cytidine diphosphate) (ammonium salt)
经验公式（希尔记法）:
C48H91N5O15P2
CAS号:
799812-77-4
分子量:
1040.21
NACRES:
NA.25

形式

liquid

包装

pkg of 1 × 1 mL (870520C-5mg)
pkg of 1 × 2.5 mL (870520C-25mg)

制造商/商品名称

Avanti Polar Lipids 870520C

浓度

10 mg/mL (870520C-25mg)
5 mg/mL (870520C-5mg)

脂质类型

phosphoglycerides
bioactive lipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)C=C2)=O)O1)([O-])=O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C48H85N3O15P2.2H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-43(52)61-37-40(64-44(53)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)38-62-67(57,58)66-68(59,60)63-39-41-45(54)46(55)47(65-41)51-36-35-42(49)50-48(51)56;;/h17-20,35-36,40-41,45-47,54-55H,3-16,21-34,37-39H2,1-2H3,(H,57,58)(H,59,60)(H2,49,50,56);2*1H3/b19-17-,20-18-;;/t40-,41-,45+,46?,47-;;/m1../s1

InChI key

NECNTGAHQCHVGS-BQGZBBTBSA-N

应用

18:1 CDP DG is suitable for liposomes preparation.

生化/生理作用

18:1 CDP DG or 1,2-dioleoyl-sn-glycero-3-(cytidine diphosphate) produces cytidine 5′?monophosphate by the reaction catalyzed by phosphatidylserine synthase (Pss). CDP-diacylglycerol is derived from diacylglycerol. It serves as a precursor in the production of phosphatidylinositides. Unregulated CDP-diacylglycerol signaling may be associated with the depression.

包装

5 mL Clear Glass Sealed Ampule (870520C-25mg)
5 mL Clear Glass Sealed Ampule (870520C-5mg)

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

易制毒化学品（2类）
危险化学品

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Kimberly R Tyeryar et al.
BMC neuroscience, 9, 12-12 (2008-01-26)
Major depression is a serious mood disorder affecting millions of adults and children worldwide. While the etiopathology of depression remains obscure, antidepressant medications increase synaptic levels of monoamine neurotransmitters in brain regions associated with the disease. Monoamine transmitters activate multiple
Andrew G Reidenbach et al.
Cell chemical biology, 25(2), 154-165 (2017-12-05)
Human COQ8A (ADCK3) and Saccharomyces cerevisiae Coq8p (collectively COQ8) are UbiB family proteins essential for mitochondrial coenzyme Q (CoQ) biosynthesis. However, the biochemical activity of COQ8 and its direct role in CoQ production remain unclear, in part due to lack
Ru-Yin Huang et al.
Current microbiology, 77(5), 710-715 (2020-01-04)
Phosphatidylserine synthase (Pss) is involved in the metabolic pathway in phospholipid synthesis in different organisms. In this study, Pss expression in Vibrio parahaemolyticus was verified through liquid chromatography tandem-mass spectrometry. To analyze the characteristics of Pss, the recombinant Pss was

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