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Merck
CN

870601C

Avanti

Azelaoyl-PAF

Avanti Research - A Croda Brand

别名:

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine

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关于此项目

经验公式(希尔记法):
C33H66NO9P
化学文摘社编号:
分子量:
651.85
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

Azelaoyl-PAF, Avanti Research - A Croda Brand 870601C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (870601C-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 870601C

concentration

1 mg/mL (870601C-1mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC(O)=O)=O)COCCCCCCCCCCCCCCCC)=O

InChI

1S/C33H66NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-23-27-40-29-31(30-42-44(38,39)41-28-26-34(2,3)4)43-33(37)25-22-19-17-18-21-24-32(35)36/h31H,5-30H2,1-4H3,(H-,35,36,38,39)/t31-/m1/s1

InChI key

ZDFOCDTXDPKJKA-WJOKGBTCSA-N

General description

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine (Azelaoyl-PAF) Azelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles. Azelaoyl-PAF is a low molecular weight phospholipid.

Application

Azelaoyl-PAF may be used in binding assay of anti-inflammatory peptides, 2F and 4F.

Biochem/physiol Actions

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine (Azelaoyl-PAF) acts as an agonist for peroxisome proliferator-activated receptors γ(PPAR-γ). It may be used as a therapeutic for Friedreich′s ataxia (FRDA). At low concentrations azelaoyl-PAF may induce apoptosis.

Packaging

5 mL Clear Glass Sealed Ampule (870601C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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