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Merck
CN

870850P

Avanti

C12 Carnitine

Avanti Research - A Croda Brand

别名:

lauroyl L-carnitine

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关于此项目

经验公式(希尔记法):
C19H37NO4
化学文摘社编号:
分子量:
343.50
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

C12 Carnitine, Avanti Research - A Croda Brand 870850P, powder

SMILES string

C[N+](C)(C)C[C@H](OC(CCCCCCCCCCC)=O)CC([O-])=O

InChI

1S/C19H37NO4/c1-5-6-7-8-9-10-11-12-13-14-19(23)24-17(15-18(21)22)16-20(2,3)4/h17H,5-16H2,1-4H3/t17-/m1/s1

InChI key

FUJLYHJROOYKRA-QGZVFWFLSA-N

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (870850P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 870850P

lipid type

bioactive lipids

shipped in

dry ice

storage temp.

−20°C

General description

C12 Carnitine or lauroyl L-carnitine, is a lauric acid-derived serum acylcarnitine. It mediates obesity-induced inflammation in adipose. Elevated levels of lauroyl carnitine in carcinoma-associated fibroblasts (CAF)-adipose tissue acts as a biomarker for obesity, insulin resistance and inflammation.

Application

C12 Carnitine or lauroyl L-carnitine has been used to investigate its effect on the glycine transporters activity. It has also been used to study its effect on pro-inflammatory activation of macrophages.

Packaging

5 mL Amber Glass Screw Cap Vial (870850P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Brante P Sampey et al.
PloS one, 7(6), e38812-e38812 (2012-06-16)
Obesity has reached epidemic proportions worldwide. Several animal models of obesity exist, but studies are lacking that compare traditional lard-based high fat diets (HFD) to "Cafeteria diets" (CAF) consisting of nutrient poor human junk food. Our previous work demonstrated the
Oleoyl-l-carnitine inhibits glycine transport by G ly T 2
Carland JE, et al.
British Journal of Pharmacology, 168(4), 891-902 (2013)

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