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经验公式(希尔记法):
C19H37NO4
化学文摘社编号:
分子量:
343.50
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C12 Carnitine, Avanti Research™ - A Croda Brand 870850P, powder
SMILES string
C[N+](C)(C)C[C@H](OC(CCCCCCCCCCC)=O)CC([O-])=O
InChI
1S/C19H37NO4/c1-5-6-7-8-9-10-11-12-13-14-19(23)24-17(15-18(21)22)16-20(2,3)4/h17H,5-16H2,1-4H3/t17-/m1/s1
InChI key
FUJLYHJROOYKRA-QGZVFWFLSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (870850P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 870850P
lipid type
bioactive lipids
shipped in
dry ice
storage temp.
−20°C
General description
C12 Carnitine or lauroyl L-carnitine, is a lauric acid-derived serum acylcarnitine. It mediates obesity-induced inflammation in adipose. Elevated levels of lauroyl carnitine in carcinoma-associated fibroblasts (CAF)-adipose tissue acts as a biomarker for obesity, insulin resistance and inflammation.
Application
C12 Carnitine or lauroyl L-carnitine has been used to investigate its effect on the glycine transporters activity. It has also been used to study its effect on pro-inflammatory activation of macrophages.
Packaging
5 mL Amber Glass Screw Cap Vial (870850P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Brante P Sampey et al.
PloS one, 7(6), e38812-e38812 (2012-06-16)
Obesity has reached epidemic proportions worldwide. Several animal models of obesity exist, but studies are lacking that compare traditional lard-based high fat diets (HFD) to "Cafeteria diets" (CAF) consisting of nutrient poor human junk food. Our previous work demonstrated the
Oleoyl-l-carnitine inhibits glycine transport by G ly T 2
Carland JE, et al.
British Journal of Pharmacology, 168(4), 891-902 (2013)
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