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经验公式（希尔记法）:
C42H84NO7P
化学文摘社编号:
分子量:
746.09
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C16-18:1 PC, Avanti Research™ - A Croda Brand 878112P, powder
InChI key
SIEDNCDNGMIKST-IYEJTHTFSA-N
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COCCCCCCCCCCCCCCCC)=O
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (878112P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 878112P
lipid type
bioactive lipids
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
Application
C16-18:1 PC or 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine may be used in the liposome binding assay. It may also be used as a lipid standard for quantification of glycerophosphocholine by liquid chromatography–mass spectrometry (LC–MS).
Biochem/physiol Actions
Platelet-activating factor (PAF), a lipid mediator acts as a pro-inflammatory agent that exhibits variety of biological and pharmacological effects.
General description
C16-18:1 PC, also called as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a member of platelet-activating factor (PAF) family of glycerophospholipids. HOPC is a mono-ether PC containing ester-linked 18:1 chain (oleoyl) at the sn-2 position and an ether-linked 16:0 chain (hexadecyl) at the sn-1 position.
Packaging
5 mL Clear Glass Sealed Ampule (878112P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Scott D Ryan et al.
Journal of lipid research, 49(10), 2250-2258 (2008-06-14)
The platelet-activating factor (PAF) family of glycerophospholipids accumulates in damaged brain tissue following injury. Little is known about the role of individual isoforms in regulating neuronal survival. Here, we compared the neurotoxic and neuroprotective activities of 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16-PAF) and 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine
John J H Shin et al.
Developmental cell, 52(4), 461-476 (2020-01-14)
Phosphoinositides, diacylglycerolpyrophosphate, ceramide-1-phosphate, and phosphatidic acid belong to a unique class of membrane signaling lipids that contain phosphomonoesters in their headgroups having pKa values in the physiological range. The phosphomonoester headgroup of phosphatidic acid enables this lipid to act as
Saki Yamaura et al.
Clinica chimica acta; international journal of clinical chemistry, 481, 184-188 (2018-03-20)
Measurement of lipoprotein-associated phospholipase A2 (Lp-PLA2) can be used as an adjunct to traditional cardiovascular risk factors for identifying individuals at higher risk of cardiovascular events. This can be performed by quantification of the protein concentration using an ELISA platform
Andrey B Imbs et al.
PloS one, 14(4), e0215759-e0215759 (2019-04-30)
To expand our knowledge of lipid and fatty acid (FA) biosynthesis in marine cnidarians, polar lipidomes of hydrocorals were studied for the first time and then compared with those of soft corals from tropical and boreal regions. The structure and
Ernst R Werner et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(14), 7792-7798 (2020-03-27)
A significant fraction of the glycerophospholipids in the human body is composed of plasmalogens, particularly in the brain, cardiac, and immune cell membranes. A decline in these lipids has been observed in such diseases as Alzheimer's and chronic obstructive pulmonary
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