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经验公式（希尔记法）:
C28H58NO7P
化学文摘社编号:
分子量:
551.74
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C18-02:0 PC, Avanti Research™ - A Croda Brand 878114P, powder
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCCCC)=O
InChI
1S/C28H58NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-33-25-28(36-27(2)30)26-35-37(31,32)34-24-22-29(3,4)5/h28H,6-26H2,1-5H3/t28-/m1/s1
InChI key
ZXCIEWBDUAPBJF-MUUNZHRXSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (878114P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 878114P
lipid type
bioactive lipids
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
Application
C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay.
Biochem/physiol Actions
C18-02:0 PC acts as a platelet-activating factor and facilitates platelet aggregation and secretion. It also plays a key role in inflammation and anaphylaxis.
General description
C18-02:0 PC, also referred as 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine, is a natural platelet-activating factor. It is found in variety of cells including, basophil leucocytes, macrophages, polymorphonuclear neutrophils and monocytes and platelets.
Packaging
5 mL Clear Glass Sealed Ampule (878114P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
Scott D Ryan et al.
Journal of lipid research, 49(10), 2250-2258 (2008-06-14)
The platelet-activating factor (PAF) family of glycerophospholipids accumulates in damaged brain tissue following injury. Little is known about the role of individual isoforms in regulating neuronal survival. Here, we compared the neurotoxic and neuroprotective activities of 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16-PAF) and 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine
Saki Yamaura et al.
Clinica chimica acta; international journal of clinical chemistry, 481, 184-188 (2018-03-20)
Measurement of lipoprotein-associated phospholipase A2 (Lp-PLA2) can be used as an adjunct to traditional cardiovascular risk factors for identifying individuals at higher risk of cardiovascular events. This can be performed by quantification of the protein concentration using an ELISA platform
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