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Merck
CN

880120P

Avanti

18:0 PEG2000 PE

Avanti Research - A Croda Brand

别名:

1,2-二硬脂酰基-sn-甘油-3-磷酸乙醇胺-N-[甲氧基(聚乙二醇)-2000](铵盐)

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化学文摘社编号:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

18:0 PEG2000 PE, Avanti Research - A Croda Brand

InChI

1S/C133H264NO55P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-131(135)186-128-130(189-132(136)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2)129-188-190(138,139)187-37-36-134-133(137)185-127-126-184-125-124-183-123-122-182-121-120-181-119-118-180-1

InChI key

QSWJINHFEMDVEM-OJCMNYADSA-N

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (880120P-1g)
pkg of 1 × 200 mg (880120P-200mg)
pkg of 1 × 25 mg (880120P-25mg)
pkg of 1 × 500 mg (880120P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

Application

18:0 PEG2000 PE可用于量子点的镍树脂官能化。它还可用于制备脂质体。

Biochem/physiol Actions

1,2-二硬脂酰-sn-丙三基-3-磷酸乙醇胺-N-[甲氧基(聚乙二醇)-2000 (18:0 PEG2000 PE)是一种有效的药物载体,具有生物相容性。PEG可以稳定并保护胶束免受吞噬系统的侵害。PEG可以作为磷脂的偶联物,改良脂质体的制备和高效药物包封。

General description

1,2-二硬脂酰-sn-丙三基-3-磷酸乙醇胺-N-[甲氧基(聚乙二醇)-2000 (18:0 PEG2000 PE)是一种偶联物,共价连接至i聚乙二醇(PEG2000)。形成以磷酸乙醇胺为疏水核心及亲水PEG2000为外胶束表面的稳定的180kDa胶束。

Packaging

20 mL透明玻璃螺旋盖小瓶(880120P-1g)
20 mL透明玻璃螺旋盖小瓶(880120帕-500毫克)
5 mL琥珀色玻璃螺旋盖小瓶(880120P-200mg)
5 mL琥珀色玻璃螺旋盖小瓶(880120P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

wgk

WGK 3


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Journal of Controlled Release : Official Journal of the Controlled Release Society, 178, 101-107 (2014)
Structure and dynamics of highly PEG-ylated sterically stabilized micelles in aqueous media
Vukovic L, et al.
Journal of the American Chemical Society, 133(34), 13481-13488 (2011)
Relationship between targeting efficacy of liposomes and the dosage of targeting antibody using surface plasmon resonance
Xiang Y, et al.
Langmuir, 31(44), 12177-12186 (2015)
P A Melnikov et al.
Bulletin of experimental biology and medicine (2019-11-24)
We studied the effect of IL-1β on the permeability of brain capillaries in healthy mice. Intravital microscopy demonstrated that parenteral administration of IL-1β was followed by an increase in vascular permeability ensuring passage of free Alexa488 fluorescent label through the
Characterization of 1, 2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[Methoxy (polyethylene glycerol)-2000] and Its Complex with Doxorubicin Using Nuclear Magnetic Resonance Spectroscopy and Molecular Dynamics
Hu W, et al.
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