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Merck
CN

880122P

Avanti

DSPE-PEG(2000) Cyanur

Avanti Research™ - A Croda Brand

别名:

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[cyanur(polyethylene glycol)-2000] (ammonium salt)

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关于此项目

化学文摘社编号:
1246304-74-4
UNSPSC Code:
12352211
NACRES:
NA.25

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产品名称

DSPE-PEG(2000) Cyanur, Avanti Research™ - A Croda Brand 880122P, powder

InChI

1S/C49H88Cl2N5O54P.25C2H4.CH4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-44(57)63-41-43(68-45(58)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)42-67-111(60,61)66-38-36-53-49(59)62-39-40-65-70-72-74-76-78-80-82-84-86-88-90-92-94-96-98-100-102-104-106-

InChI key

UOOBAWOAHDKZLJ-YDBTUDGBSA-M

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO/C=C/NC1=NC(Cl)=NC(Cl)=N1)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (880122P-10mg), pkg of 1 × 50 mg (880122P-50mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880122P

shipped in

dry ice

storage temp.

−20°C

General description

DSPE-PEG(2000) Cyanur is a conjugate of cationic lipid DSPE-PEG (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol) and cyanuric groups.

Application

DSPE-PEG has been used in the preparation of cationic liposome. It has also been used to suspend single-walled carbon nanotubes.

Packaging

5 mL Amber Glass Screw Cap Vial (880122P-10mg)
5 mL Amber Glass Screw Cap Vial (880122P-50mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

wgk

WGK 3

法规信息

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MicroRNA Targeted Cancer Therapy, 110-110 (2014)
Protein-targeted corona phase molecular recognition
Bisker G, et al.
Nature Communications, 7, 10241-10241 (2016)
Targeted delivery of let-7a microRNA encapsulated ephrin-A1 conjugated liposomal nanoparticles inhibit tumor growth in lung cancer
Lee HY, et al.
International journal of nanomedicine, 8, 4481-4481 (2013)
Heike Bakowsky et al.
Biochimica et biophysica acta, 1778(1), 242-249 (2007-10-30)
Carbohydrate moieties of the cellular glycocalyx have been suggested to play an important role in biological recognition processes during pathologic conditions, such as inflammation and cancer. Herein, we describe lectin-modified liposomes which might have potential for site-specific drug delivery during
G Bendas et al.
International journal of pharmaceutics, 181(1), 79-93 (1999-06-17)
In order to develop long-circulating immunoliposomes (IL), which combine sterical stabilization with a superior targetability, we have introduced a new methodology for attaching monoclonal antibodies directly onto the distal ends of liposome-grafted polyethylene glycol (PEG) chains. Therefore, we have synthesized
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