产品名称
DSPE-PEG (2000) 叶酸, Avanti Research™ - A Croda Brand 880124P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (880124P-1mg), pkg of 1 × 10 mg (880124P-10mg), pkg of 1 × 5 mg (880124P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 880124P
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OCCNC(OCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO/C=C\NC(CC[C@H](NC(C1=CC=C(NCC(C=N2)=NC3=C2N=C(N)NC3=O)C=C1)=O)C([O-])=O)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C
Application
将 DSPE-PEG (2000) 叶酸在氯仿中混合，制备叶酸靶向的聚乙二醇化脂质体。
Biochem/physiol Actions
叶酸盐对妊娠期巨幼红细胞性贫血有保护作用。
Packaging
5 mL 棕色玻璃螺旋盖小瓶 (880124P-1 mg)
5 mL 棕色玻璃螺旋盖小瓶 (880124P-10 mg)
5 mL 棕色玻璃螺旋盖小瓶 (880124P-5 mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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存储类别
11 - Combustible Solids
Microfluidic synthesis of PEG-and folate-conjugated liposomes for one-step formation of targeted stealth nanocarriers
Hood RR, et al.
Pharmaceutical Research, 30(6), 1597-1607 (2013)
Folate and human reproduction.
Tamura T and Picciano MF
American Journal of Clinical Nutrition, 83(5), 993-1016 (2006)
A Gabizon et al.
Bioconjugate chemistry, 10(2), 289-298 (1999-03-17)
Conjugates of three components, folic acid-poly(ethylene glycol)-distearoylphosphatidylethanolamine (FA-PEG-DSPE), derived from PEG with molecular masses of 2000 and 3350 Da were synthesized by a carbodiimide-mediated coupling of FA to H2N-PEG-DSPE. The conjugates were characterized by 1H NMR, MALDI-TOF, and HPLC analysis
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 880124P-5MG | 04061835187492 |
| 880124P-1MG | 04061835187485 |
| 880124P-10MG | 04061835187478 |