Product Name
DSPE-PEG(2000) Folate, Avanti Research™ - A Croda Brand
表单
liquid
包装
pkg of 1 × 1 mL (880124X-10mg)
pkg of 1 × 1 mL (880124X-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
浓度
1 mg/mL (880124X-1mg)
10 mg/mL (880124X-10mg)
运输
dry ice
储存温度
−20°C
一般描述
DSPE-PEG(2000) Folate, also known as 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000], is a functionalized PEG lipid. This lipid is added into liposomes as a targeting ligand for folate receptors, which acts as cellular surface markers for numerous solid tumors and myeloid leukemias. Folate targeted drug delivery is used an effective therapy for the treatment and imaging of various cancers and inflammatory diseases. Folate conjugates with low molecular weight and high binding affinity for folate receptors (FR) on cell surface deliver a variety of molecular complexes such as protein toxins, immune stimulants, chemotherapeutic agents, liposomes, nanoparticles, and imaging agents to pathologic cells without affecting normal tissues.
应用
DSPE-PEG(2000) Folate(1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-2000]) may be used in preparation of folate-conjugated liposomes and folate-modified microvesicles (MVs).
包装
5 mL Clear Glass Sealed Ampule (880124X-10mg)
5 mL Clear Glass Sealed Ampule (880124X-1mg)
制备说明
Soluble in ethanol, DMSO, and Chloroform:Methanol:Ammonia (80:20:2) at 5mg/mL
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 2 - STOT SE 3
靶器官
Eyes,Central nervous system, Liver,Kidney, Respiratory system
储存分类代码
3 - Flammable liquids
WGK
WGK 3
闪点(°F)
80.6 °F
闪点(°C)
27 °C
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