产品名称
18:1 PEG5000 PE, Avanti Research™ - A Croda Brand 880230C
SMILES string
[H][C@@](COP([O-])(OCCNC([(OCH2CH2)113OCH3])=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (880230C-25mg)
pkg of 2 × 4 mL (880230C-200mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 880230C
concentration
10 mg/mL (880230C-25mg)
25 mg/mL (880230C-200mg)
shipped in
dry ice
storage temp.
−20°C
Application
18:1 PEG5000 PE or 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 has been used in small unilamellar vesicles (SUV).
Biochem/physiol Actions
18:1 PEG5000 PE, also known as 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000], is used along with lipid modified dendrimer copolymer to co-deliver siRNA and drugs to tumors.
Packaging
5 mL Clear Glass Sealed Ampule (880230C-200mg)
5 mL Clear Glass Sealed Ampule (880230C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
target_organs
Liver,Kidney, Respiratory system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
危险化学品
易制毒化学品(2类)
此项目有
TCR--pMHC bond conformation controls TCR ligand discrimination
Sasmal DK, et al.
Cellular & Molecular Immunology, 65-76 (2017)
Xiaolei Su et al.
Methods in molecular biology (Clifton, N.J.), 1584, 65-76 (2017-03-04)
Biochemical reconstitution has served as an important tool for understanding the mechanisms of many cellular processes including DNA replication, transcription, translation, vesicle trafficking, and ubiquitin-mediated proteolysis. Here, we demonstrate that biochemical reconstitution can be applied to studying a complex signaling
Dibyendu K Sasmal et al.
Cellular & molecular immunology, 17(3), 203-217 (2019-09-19)
A major unanswered question is how a TCR discriminates between foreign and self-peptides presented on the APC surface. Here, we used in situ fluorescence resonance energy transfer (FRET) to measure the distances of single TCR-pMHC bonds and the conformations of
Reconstitution of TCR signaling using supported lipid bilayers
Su X, et al.
Methods in Molecular Biology (2017)
Jiayi Pan et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 136, 18-28 (2019-01-12)
Multidrug resistance (MDR) significantly decreases the therapeutic efficiency of anti-cancer drugs. Its reversal could serve as a potential method to restore the chemotherapeutic efficiency. Downregulation of MDR-related proteins with a small interfering RNA (siRNA) is a promising way to reverse
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