SMILES string
O=C(NCC(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C)C(CCN1C(C=CC1=O)=O)=O)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=
biological source
synthetic
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (880267P-10MG)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
polymerizable lipids
shipped in
dry ice
storage temp.
−20°C
General description
DSG-pSar25-Mal is a lipid that is composed of a DSG unit conjugated to a pSar25 polymer. Polysarcosine (pSar) lipids are offered as alternatives to traditional PEGylated lipids used in RNA delivery vehicles. Compared to similar PEGylated lipid nanoparticles (LNPs), pSar LNPs have shown improved mRNA transfection potency and improved safety profiles.
Application
Targeted Drug Delivery
Features and Benefits
This compound features a maleimide group enabling a highly versatile platform for bioconjugation. The maleimide group reacts with thiol groups on peptides, facilitating the attachment of bioactive molecules to the lipid nanoparticle surface. This unique capability allows for the creation of LNPs tailored for targeted delivery to specific cells.
Packaging
5 mL Amber Glass Screw Cap Vial (880267P-10MG)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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