产品名称
18:1 PEG350 PE, Avanti Research™ - A Croda Brand 880430O
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 25 mg (880430O-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 880430O
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]
InChI
1S/C57H108NO17P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-55(59)72-52-54(75-56(60)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2)53-74-76(62,63)73-37-36-58-57(61)71-51-50-70-49-48-69-47-46-68-45-44-67-43-42-66-41-40-65-39-38-64-3;/h18-21,54H,4-1
InChI key
JIOGNAWOCNOXPY-VYAKHVMVSA-N
General description
18:0 PEG350 PE is a polyethylene glycol (PEG) conjugated phospholipid. PEGylated phospholipids are amphiphilic polymers, The molecular weight and exact mass are averages based on the polydispersity of PEG.
Application
18:1 PEG350 PE is suitable for use:
- in the preparation of lipid bilayer membranes to estimate the diameter of the ion channel formed by the Bacillus anthracis protective antigen 63 (PA63)
- to prepare Gd-C5F12-phospholipid nanobubbles
- to form aqueous dispersions and to study metal cation induced cubic phase
Biochem/physiol Actions
Polyethylene glycol (PEG) conjugated phospholipids are known to protect the steric nature of liposomes. Hence, they are commonly recommended for use in liposome formulation. PEGylated lipids are used as drug carriers. Use of highly concentrated PEG-lipids makes the possibility of mixed micelles.
Packaging
5 mL Clear Glass Sealed Ampule (880430O-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
10 - Combustible liquids
wgk
WGK 3
Micro- and Nanoengineering of the Cell Surface (2014)
Michela Pisani et al.
The journal of physical chemistry. B, 112(17), 5276-5278 (2008-04-11)
Metal cations (Mn(2+) or Ca(2+)) in aqueous dispersions of mixtures of dioleoylphosphatidylethanolamine (DOPE) and poly(ethylene glycol)-functionalized DOPE (DOPE-PEG(350)) induce, above a certain amount of the PEG lipid component, a phase transition from the inverted hexagonal phase H(II) to the bicontinuous
Se-Young Choi et al.
PloS one, 7(3), e34333-e34333 (2012-04-06)
To develop a long-circulating theragnostics, meaning therapeutics and diagnostics for MR-guided HIFU ablation, we designed and prepared Gd-C(5)F(12)-phospholipid nanobubbles (PLNs) 30-100 nm in diameter. The biochemical and physical characterization of Gd-C(5)F(12)-PLNs were performed. Since Gd-C(5)F(12)-PLN-50 (Φ = 50 nm) and Gd-C(5)F(12)-PLN-100 (Φ = 100
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 880430O-25MG | 04061835192458 |