Merck
CN

880720P

Avanti

18:0 PEG1000 PE

Avanti Polar Lipids 880720P, powder

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别名:
1,2-二硬脂酰-sn-甘油-3-磷酸乙醇胺-N-[甲氧基(聚乙二醇)-1000](铵盐)
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 200 mg (880720P-200mg)
pkg of 1 × 25 mg (880720P-25mg)

manufacturer/tradename

Avanti Polar Lipids 880720P

运输

dry ice

储存温度

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]

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此商品
880720C880220P880120C
18:0 PEG1000 PE Avanti Polar Lipids 880720P, powder

Avanti

880720P

18:0 PEG1000 PE

18:0 PEG1000 PE Avanti Polar Lipids 880720C

Avanti

880720C

18:0 PEG1000 PE

18:0 PEG5000 PE Avanti Polar Lipids 880220P, powder

Avanti

880220P

18:0 PEG5000 PE

18:0 PEG2000 PE Avanti Polar Lipids 880120C

Avanti

880120C

18:0 PEG2000 PE

packaging

pkg of 1 × 200 mg (880720P-200mg), pkg of 1 × 25 mg (880720P-25mg)

packaging

pkg of 1 × 2.5 mL (880720C-25mg), pkg of 2 × 4 mL (880720C-200mg)

packaging

pkg of 1 × 1 g (880220P-1g), pkg of 1 × 200 mg (880220P-200mg), pkg of 1 × 25 mg (880220P-25mg), pkg of 1 × 500 mg (880220P-500mg)

packaging

pkg of 1 × 2.5 mL (880120C-25mg), pkg of 1 × 20 mL (880120C-500mg), pkg of 2 × 4 mL (880120C-200mg)

manufacturer/tradename

Avanti Polar Lipids 880720P

manufacturer/tradename

Avanti Polar Lipids 880720C

manufacturer/tradename

Avanti Polar Lipids 880220P

manufacturer/tradename

Avanti Polar Lipids 880120C

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

一般描述

分子量和精确质量是基于聚乙二醇(PEG)的多分散性的平均值。

应用

1,2-二硬脂酰-sn-甘油-3-磷酸乙醇胺-N-[甲氧基(聚乙二醇)-1000](18:0 PEG1000 PE)可用于制备空间稳定脂质体,并通过小角度X线检查散射(SAXS)法研究其特性。它也适用于无胆固醇的聚乙二醇化(CF-PEG)脂质体,以研究其在装载亲水性药物卡铂时的长期稳定性。

生化/生理作用

磷脂乙醇胺(PE)是细胞膜上几种磷脂的底物。它与磷脂周转有关。PE也被发现可以阻止肿瘤进展。

包装

5 mL棕色玻璃螺旋盖小瓶(880720P-200mg)
5 mL棕色玻璃螺旋盖小瓶(880720P-25mg)

储存分类代码

11 - Combustible Solids

WGK

WGK 3


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Z Varga et al.
Chemistry and physics of lipids, 165(4), 387-392 (2012-01-10)
Synchrotron small-angle X-ray scattering analysis of the bilayer structure of a pharmacologically relevant sterically stabilized liposome system is presented. Describing the electron density profile of the bilayer with the superposition of Gaussian functions, the contribution of the poly(ethylene glycol) (PEG)
Adilson Kleber Ferreira et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 67(6), 481-487 (2013-06-19)
Phosphoethanolamine (Pho-s) is a compound involved in phospholipid turnover, acting as a substrate for many phospholipids of the cell membranes. In a recent study, we showed that Pho-s has antitumor effect in the several tumor cells. In this study we
Anumita Chaudhury et al.
International journal of pharmaceutics, 430(1-2), 167-175 (2012-04-28)
The obstacles in translating liposome formulations into marketable products could be attributed to their physical instabilities upon long-term storage as aqueous dispersions. Lyophilization is the most commonly used technique to improve physical stability of liposomes. The development of stable, lyophilized
Brian J Nablo et al.
Biophysical journal, 95(3), 1157-1164 (2008-07-23)
Nonelectrolyte polymers of poly(ethylene glycol) (PEG) were used to estimate the diameter of the ion channel formed by the Bacillus anthracis protective antigen 63 (PA(63)). Based on the ability of different molecular weight PEGs to partition into the pore and

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