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Merck
CN

880730C

Avanti

18:1 PEG1000 PE

Avanti Research™ - A Croda Brand

别名:

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] (ammonium salt)

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关于此项目

化学文摘社编号:
474922-90-2
UNSPSC Code:
12352211
NACRES:
NA.25

主要文件

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产品名称

18:1 PEG1000 PE, Avanti Research™ - A Croda Brand 880730C

InChI key

GAPHFOOXSGWGKG-QOYAZRIPSA-N

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (880730C-25mg)
pkg of 2 × 4 mL (880730C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880730C

concentration

10 mg/mL (880730C-25mg)
25 mg/mL (880730C-200mg)

shipped in

dry ice

storage temp.

−20°C

Application

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] (18:1 PEG1000 PE) is suitable for fluorescent PEG-grafted liposomes/fluorescent stealth liposomes or liposomes.

Biochem/physiol Actions

Polyethylene glycol (PEG) conjugated phospholipids are known to protect the steric nature of liposomes. Hence, they are commonly recommended for use in liposome formulation.

Packaging

5 mL Clear Glass Sealed Ampule (880730C-200mg)
5 mL Clear Glass Sealed Ampule (880730C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

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分析证书(COA)

Lot/Batch Number

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Surface-grafted polyethylene glycol conformation impacts the transport of PEG-functionalized liposomes through a tumour extracellular matrix model
Labouta HI, et al.
Royal Society of Chemistry Advances, 8(14), 7697-7708 (2018)
Have Aliu et al.
International journal of nanomedicine, 12, 8377-8388 (2017-12-05)
Immunotherapy by sublingual administration of allergens provides high patient compliance and has emerged as an alternative to subcutaneous immunotherapy for the treatment of IgE-associated allergic diseases. However, sublingual immunotherapy (SLIT) can cause adverse events. Development of allergen delivery systems enabling
G F Peacock et al.
Drug delivery, 10(1), 29-34 (2003-01-30)
A new cholesterol-carborane conjugate (BCH) has been synthesized as a potential targeting agent for boron neutron capture therapy (BNCT) of cancers. The compound is extremely water insoluble and was formulated in two liposomal formulations to determine if the compound could
Maria C Sandström et al.
Langmuir : the ACS journal of surfaces and colloids, 23(8), 4192-4198 (2007-03-09)
Polyethylene glycol (PEG)-conjugated lipids are commonly employed for steric stabilization of liposomes. When added in high concentrations PEG-lipids induce formation of mixed micelles, and depending on the lipid composition of the sample, these may adapt either a discoidal or a

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