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Merck
CN

890704C

Avanti

18:1 EPC (Cl Salt)

Avanti Research - A Croda Brand

别名:

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)

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关于此项目

经验公式(希尔记法):
C46H89NO8PCl
化学文摘社编号:
分子量:
850.63
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

18:1 EPC (Cl Salt), Avanti Research - A Croda Brand

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (890704C-25mg), pkg of 1 × 4 mL (890704C-100mg), pkg of 2 × 4 mL (890704C-200mg)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

10 mg/mL (890704C-25mg), 25 mg/mL (890704C-100mg), 25 mg/mL (890704C-200mg)

application(s)

advanced drug delivery

lipid type

transfection
cationic lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)OCC.[Cl-]

InChI key

LXTQBOAODSPEHG-NATHRRJOSA-M

General description

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) is a cationic alkylated phospholipid.

Application

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt) (18:1 EPC (Cl Salt)) is suitable:
  • for composing lipid shell to prepare lipopolyplex/mRNA vaccine
  • in solvent-assisted preparation of supported lipid bilayers
  • along with 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) in mixed liposomes as colloidal vectors for physicochemical study of the DNA compaction
  • to formulate the lipid nanoparticle (LNP1) to enhance intracellular delivery mediated by shock waves

Biochem/physiol Actions

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) serves as a transfection reagent. 18:1 EPC is applicable in liposomes and lipoplexes. It is a potential vector in gene therapy.

Packaging

5 mL Clear Glass Sealed Ampule (890704C-100mg)
5 mL Clear Glass Sealed Ampule (890704C-200mg)
5 mL Clear Glass Sealed Ampule (890704C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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