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Merck
CN

890705P

Avanti

16:0-18:1 EPC (Cl Salt)

Avanti Research - A Croda Brand

别名:

1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)

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关于此项目

经验公式(希尔记法):
C44H87NO8PCl
化学文摘社编号:
分子量:
824.59
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

16:0-18:1 EPC (Cl Salt), Avanti Research - A Croda Brand

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (890705P-10mg), pkg of 1 × 25 mg (890705P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand

application(s)

advanced drug delivery

lipid type

transfection
cationic lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)OCC.[Cl-]

InChI

1S/C44H87NO8P.ClH/c1-7-10-12-14-16-18-20-22-23-25-27-29-31-33-35-37-44(47)53-42(41-52-54(48,50-9-3)51-39-38-45(4,5)6)40-49-43(46)36-34-32-30-28-26-24-21-19-17-15-13-11-8-2;/h22-23,42H,7-21,24-41H2,1-6H3;1H/q+1;/p-1/b23-22-;/t42-,54?;/m1./s1

InChI key

SXRDCCSKGWBZFF-ISBKSCLYSA-M

General description

1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (16:0-18:1 EPC) is cationic lipid containing an ethyl group attached to the phosphate moiety through an ester bond and has a choline headgroup.

Application

1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (chloride salt) (16:0-18:1 EPC (Cl Salt)) might be used:
  • as a cationic lipid to explore the change in organization and dynamics of a membrane-bound fluorescent probe in host membranes of varying charge
  • in the preparation of small unilamellar cationic liposomes
  • in a novel albumin-associated lipoplex formulation to evaluate the antitumoral efficacy of immuno-gene therapy and “suicide” gene therapy

Biochem/physiol Actions

1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (16:0-18:1 EPC) is a potential transfection agent, which is also similar to the natural lipids.

Packaging

5 mL Clear Glass Sealed Ampule (890705P-10mg)
5 mL Clear Glass Sealed Ampule (890705P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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存储类别

11 - Combustible Solids



历史批次信息供参考:

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