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关于此项目
经验公式(希尔记法):
C44H87NO8PCl
化学文摘社编号:
分子量:
824.59
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
16:0-18:1 EPC (Cl Salt), Avanti Research™ - A Croda Brand
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (890705P-10mg), pkg of 1 × 25 mg (890705P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
application(s)
advanced drug delivery
lipid type
transfection
cationic lipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)OCC.[Cl-]
InChI
1S/C44H87NO8P.ClH/c1-7-10-12-14-16-18-20-22-23-25-27-29-31-33-35-37-44(47)53-42(41-52-54(48,50-9-3)51-39-38-45(4,5)6)40-49-43(46)36-34-32-30-28-26-24-21-19-17-15-13-11-8-2;/h22-23,42H,7-21,24-41H2,1-6H3;1H/q+1;/p-1/b23-22-;/t42-,54?;/m1./s1
InChI key
SXRDCCSKGWBZFF-ISBKSCLYSA-M
General description
1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (16:0-18:1 EPC) is cationic lipid containing an ethyl group attached to the phosphate moiety through an ester bond and has a choline headgroup.
Application
1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (chloride salt) (16:0-18:1 EPC (Cl Salt)) might be used:
- as a cationic lipid to explore the change in organization and dynamics of a membrane-bound fluorescent probe in host membranes of varying charge
- in the preparation of small unilamellar cationic liposomes
- in a novel albumin-associated lipoplex formulation to evaluate the antitumoral efficacy of immuno-gene therapy and “suicide” gene therapy
Biochem/physiol Actions
1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (16:0-18:1 EPC) is a potential transfection agent, which is also similar to the natural lipids.
Packaging
5 mL Clear Glass Sealed Ampule (890705P-10mg)
5 mL Clear Glass Sealed Ampule (890705P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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存储类别
11 - Combustible Solids