890850O
Avanti
18:1 DAP
Avanti Research™ - A Croda Brand
别名:
1,2-二油酰-3-二甲基铵-丙烷(DODAP)
表单
liquid
包装
pkg of 2 × 100 mg (890850O-200mg)
pkg of 1 × 25 mg (890850O-25mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
脂质类型
cationic lipids
transfection
运输
dry ice
储存温度
−20°C
SMILES字符串
[H]C(CN(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O
InChI
1S/C41H77NO4/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-40(43)45-38-39(37-42(3)4)46-41(44)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h19-22,39H,5-18,23-38H2,1-4H3/b21-19-,22-20-
InChI key
NYDLOCKCVISJKK-WRBBJXAJSA-N
一般描述
18:1 DAP是一种阳离子脂质,制备阳离子脂质体。
应用
18:1 DAP适用于:
- 作为脂质双分子层的组分
- 制备稳定的核酸脂质囊泡
- 含反义寡脱氧核糖核苷酸(ODN)的叶酸(FA)靶向脂质体和非靶向脂质体的制备和理化特性表征
包装
5 mL透明玻璃密封安瓿瓶(890850O-200mg)
5 mL透明玻璃密封安瓿瓶(890850O-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
10 - Combustible liquids
WGK
WGK 3
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BioMed Research International, 2014 (2014)
Nonequilibrium adhesion patterns at lipid bilayer junctions
Parthasarathy R, et al.
The Journal of Physical Chemistry B, 108(2), 649-657 (2004)
Qiang Cheng et al.
Nature nanotechnology, 15(4), 313-320 (2020-04-07)
CRISPR-Cas gene editing and messenger RNA-based protein replacement therapy hold tremendous potential to effectively treat disease-causing mutations with diverse cellular origin. However, it is currently impossible to rationally design nanoparticles that selectively target specific tissues. Here, we report a strategy
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