跳转至内容
Merck
CN

主要文件

查看所有文档

890890C

Avanti

18:1 TAP (DOTAP)

Avanti Research™ - A Croda Brand

别名:

1,2-二油酰基-3-三甲基铵-丙烷 (氯盐)

登录 查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:
C42H80NO4Cl
化学文摘社编号:
132172-61-3
分子量:
698.54
MDL number:
MFCD01310872
UNSPSC Code:
12352211
NACRES:
NA.25
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (890890C-25mg), pkg of 2 × 20 mL (890890C-1g), pkg of 2 × 4 mL (890890C-200mg), pkg of 5 × 4 mL (890890C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

10 mg/mL (890890C-25mg), 25 mg/mL (890890C-1g), 25 mg/mL (890890C-200mg), 25 mg/mL (890890C-500mg)

application(s)

advanced drug delivery

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Cl-]

InChI

1S/C42H80NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,40H,6-19,24-39H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-;

InChI key

KSXTUUUQYQYKCR-LQDDAWAPSA-M

Application

18:1 TAP (DOTAP) 已用于制备脂质体支持的双层。

Biochem/physiol Actions

18:1 TAP (DOTAP) 为阳离子脂质结构，用于体内和体外核酸和蛋白递送。脂质组成和细胞类型会影响 DOTAP （1,2-二油酰基-3-三甲基铵-丙烷）的转染潜能。18:1 TAP（DOTAP）介导造血干细胞（HSCs）的基因敲低技术。

Packaging

30 mL 带螺旋盖的琥珀色窄口玻璃瓶（890890C-1g）
5 mL透明玻璃密封安瓿（890890C-200mg）
5 mL透明玻璃密封安瓿（890890C-25mg）
5 mL透明玻璃密封安瓿（890890C-500mg）

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Still not finding the right product?

Explore all of our products under 18:1 TAP (DOTAP)

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

危险化学品
易制毒化学品（2类）

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助，请联系 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Mesoporous silica-supported lipid bilayers (protocells) for DNA cargo delivery to the spinal cord
Dengler EC, et al.
J. Controlled Release, 168(2), 209-224 (2013)
DOTAP (and other cationic lipids): chemistry, biophysics, and transfection
Simberg D, et al.
Critical Reviews in Therapeutic Drug Carrier Systems, 21(4) (2004)
Wen Xiao et al.
Molecular pharmaceutics, 17(1), 229-238 (2019-11-26)
Eukaryotic translation initiation factors 3i (eIF3i) is a proto-oncogene that is overexpressed in various tumors, reducing its expression by eIF3i shRNA is a promising strategy to inhibit tumor growth or metastasis. Tumor cell is the target of eIF3i shRNA so
查看所有相关文献

全球贸易项目编号

货号GTIN
890890C-25MG04061837668982
890890C-200MG04061837668975
890890C-500MG04061837668999
890890C-1G04061837668968