产品名称
PGE1, Avanti Research™ - A Croda Brand 900100P, powder
SMILES string
O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1
InChI
1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1
InChI key
GMVPRGQOIOIIMI-DWKJAMRDSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (900100P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 900100P
lipid type
neutral glycerides
neutral lipids
shipped in
dry ice
storage temp.
−20°C
Application
前列腺素E1（PGE1）可用于研究其形成银加合物的能力。它也适用于趋化性测定。
Biochem/physiol Actions
前列腺素（PG）介导血管舒张和血管收缩，前列腺素E系列是一种高效的血管舒张剂。它有效地引起红斑。PGE1被认为是强效的致热因子（pyretic factor），并通过脑室起作用。它可用于在手术前延长患有导管依赖型先天性心脏病的新生儿的心血管功能。它可用作血管扩张剂。在精子中PGE1显示出孕激素诱导的Ca2 +瞬变。
General description
前列腺素（PGs）属于类花生酸（eicosanoid）类生物化合物，是花生四烯酸代谢过程中形成的氧衍生物。PG位于哺乳动物的每一种组织和体液中。它首先在人类前列腺中被发现，因此得名前列腺素。
Packaging
5 mL琥珀色玻璃螺旋盖小瓶（900100P-1mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Polina V Lishko et al.
Nature, 471(7338), 387-391 (2011-03-18)
Steroid hormone progesterone released by cumulus cells surrounding the egg is a potent stimulator of human spermatozoa. It attracts spermatozoa towards the egg and helps them penetrate the egg's protective vestments. Progesterone induces Ca(2+) influx into spermatozoa and triggers multiple
Erminia Bentivegna et al.
Le infezioni in medicina, 23(1), 69-73 (2015-03-31)
Prostaglandins appear to reduce biofilm formation and chronicization of infections, and stimulate a rapid and effective clearance of infecting micro-organisms. We report a case of recovery from methicillin-susceptible Staphylococcus aureus (MSSA) osteomyelitis after multidisciplinary management with antibiotics, anti-thrombotics and prostaglandin
Alper Aykanat et al.
Pediatric cardiology, 37(1), 131-134 (2015-08-12)
Prostaglandin E1 is crucial for keeping the patent ductus arteriosus in critical congenital heart disease for the survival and palliation of particularly prematurely born babies until a cardiosurgical intervention is available. In this study, the side effects of prostaglandin E1
Ayanna U Jackson et al.
Analytical and bioanalytical chemistry, 399(1), 367-376 (2010-11-12)
Spray solvent doped with silver ions increases the ease of olefin detection by desorption electrospray ionization (DESI). Characteristic silver adducts were generated in up to 50 times greater abundance when compared to conventional DESI spray solvents for the biologically significant
The Prostaglandins (2013)
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