900400P
Avanti
棕榈酸（15-yne）
Avanti Research™ - A Croda Brand
别名:
十六碳炔酸
产品名称
棕榈酸（15-yne）, Avanti Research™ - A Croda Brand 900400P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (900400P-1mg)
pkg of 1 × 5 mg (900400P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 900400P
脂质类型
click reagents
运输
dry ice
储存温度
−20°C
SMILES字符串
OC(CCCCCCCCCCCCCC#C)=O
InChI
1S/C16H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h1H,3-15H2,(H,17,18)
InChI key
PUZGUNYANHPRKM-UHFFFAOYSA-N
应用
棕榈酸 (15-yne) 已用作脂肪酸探针储备溶液的一种成分，用于优化 Alk-C16 与细胞蛋白的结合。它也适用于代谢标记。
生化/生理作用
炔基棕榈酸 (aPA) 是一种改性棕榈酸，带有一个ω末端炔烃。末端炔烃基团可用于与含叠氮化物试剂的高度特异性连接反应，这被称为“点击化学”′。点击化学反应快速、方便、用途广泛且具有区域特异性。它们很容易纯化。 aPA 可用于分离棕榈酰化蛋白质。
包装
5 mL棕色玻璃螺旋盖小瓶（900400P-1mg）
5 mL棕色玻璃螺旋盖小瓶（900400P-5mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
Christopher D Hein et al.
Pharmaceutical research, 25(10), 2216-2230 (2008-05-30)
Click chemistry refers to a group of reactions that are fast, simple to use, easy to purify, versatile, regiospecific, and give high product yields. While there are a number of reactions that fulfill the criteria, the Huisgen 1,3-dipolar cycloaddition of
Keri A Tallman et al.
Journal of lipid research, 54(3), 859-868 (2013-01-12)
Monitoring lipid distribution and metabolism in cells and biological fluids poses many challenges because of the many molecular species and metabolic pathways that exist. This study describes the synthesis and study of molecules that contain an alkyne functional group as
Christoph Thiele et al.
ACS chemical biology, 7(12), 2004-2011 (2012-09-25)
Fatty acids are abundant constituents of all biological systems, and their metabolism is important for normal function at all levels of an organism. Aberrations in fatty acid metabolism are associated with pathological states and have become a focus of current
Stephen B Milne et al.
Nature chemical biology, 6(3), 205-207 (2010-01-26)
Alkyne-modified phospholipids can be unambiguously identified and differentiated from native species in complex mixtures by formation of dicobalthexacarbonyl complexes. This reaction is specific for alkynes and is unaffected by other glycerophospholipid-related moieties. Enrichment of cells with alkyne-derivatized fatty acids or
Alexander L Ticho et al.
The Journal of biological chemistry, 295(14), 4488-4497 (2020-02-20)
The ileal apical sodium-dependent bile acid transporter (ASBT) is crucial for the enterohepatic circulation of bile acids. ASBT function is rapidly regulated by several posttranslational modifications. One reversible posttranslational modification is S-acylation, involving the covalent attachment of fatty acids to
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