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Merck
CN

999984C

Avanti

4ME 16:0 Diether PC

Avanti Research - A Croda Brand

别名:

1,2-di-O-phytanyl-sn-glycero-3-phosphocholine

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关于此项目

经验公式(希尔记法):
C48H100NO6P
化学文摘社编号:
分子量:
818.28
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

4ME 16:0 Diether PC, Avanti Research - A Croda Brand 999984C

InChI

1S/C48H100NO6P/c1-40(2)20-14-22-42(5)24-16-26-44(7)28-18-30-46(9)32-35-52-38-48(39-55-56(50,51)54-37-34-49(11,12)13)53-36-33-47(10)31-19-29-45(8)27-17-25-43(6)23-15-21-41(3)4/h40-48H,14-39H2,1-13H3/t42?,43?,44?,45?,46?,47?,48-/m1/s1

InChI key

NMRGXROOSPKRTL-SUJDGPGCSA-N

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCC(C)CCCC(C)CCCC(C)CCCC(C)C)COCCC(C)CCCC(C)CCCC(C)CCCC(C)C)=O

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (999984C-10mg)

manufacturer/tradename

Avanti Research - A Croda Brand 999984C

concentration

10 mg/mL (999984C-10mg)

lipid type

phospholipids

shipped in

dry ice

storage temp.

−20°C

Packaging

5 mL Clear Glass Sealed Ampule (999984C-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Application

4ME 16:0 Diether PC or 1,2-di-O-phytanyl-sn-glycero-3-phosphocholine is suitable for the preparation of multilamellar and giant lipid vesicles. It has also been used as a standard to analyze and compare the archaeal abundances in microbial communities based on the phosphoether lipids (PEL) concentrations.

Biochem/physiol Actions

Ether lipids are components of membrane structure, influencing the fluidity and fusion of biological membranes. They possess antioxidative action and helps reducing oxidative stress. Cell differentiation and cellular signaling are some of the other physiological processes controlled by ether lipids.

General description

4ME 16:0 Diether PC or 1,2-di-O-phytanyl-sn-glycero-3-phosphocholine is an archaeal phospholipid having two phytane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

wgk

WGK 3

法规信息

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ZhangFei Su et al.
Langmuir : the ACS journal of surfaces and colloids, 34(21), 6249-6260 (2018-05-04)
The insertion and ion-conducting channel properties of alamethicin reconstituted into a 1,2-di- O-phytanyl- sn-glycero-3-phosphocholine bilayer floating on the surface of a gold (111) electrode modified with a 1-thio-β-d-glucose (β-Tg) self-assembled monolayer were investigated using a combination of electrochemical impedance spectroscopy
S A Carr et al.
Geobiology, 11(4), 377-395 (2013-05-21)
Marine sediments of the Ross Sea, Antarctica, harbor microbial communities that play a significant role in the decomposition, mineralization, and recycling of organic carbon (OC). In this study, the cell densities within a 153-cm sediment core from the Ross Sea
Marta Salvador-Castell et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183130-183130 (2019-11-18)
It is now well established that cell membranes are much more than a barrier that separate the cytoplasm from the outside world. Regarding membrane's lipids and their self-assembling, the system is highly complex, for example, the cell membrane needs to
Vid Šuštar et al.
PloS one, 7(7), e39401-e39401 (2012-07-14)
As variance from standard phospholipids of eubacteria and eukaryotes, archaebacterial diether phospholipids contain branched alcohol chains (phytanol) linked to glycerol exclusively with ether bonds. Giant vesicles (GVs) constituted of different species of archaebacterial diether phospholipids and glycolipids (archaeosomes) were prepared
John M Dean et al.
Protein & cell, 9(2), 196-206 (2017-05-20)
Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether bond, as opposed to an ester bond in the more common diacyl phospholipids. This

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