产品名称
18:0 Diether PC, 1,2-di-O-octadecyl-sn-glycero-3-phosphocholine, powder
InChI key
HVVJCLFLKMGEIY-USYZEHPZSA-N
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCCCCCCCC)COCCCCCCCCCCCCCCCCCC)=O
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (999991P-10mg)
pkg of 1 × 500 mg (999991P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 999991P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
Application
18:0 Diether PC or 1,2-di-O-octadecyl-sn-glycero-3-phosphocholine might be used:
- as a nonhydrolizable ether lipid in calcein-containing vesicles for calcein encapsulation
- to prepare ether-linked phospholipid bilayer membrane for examining its thermotropic and barotropic phase transitions
- as a component of internal standard mixture for lipid extraction from plasma sample using mass spectromety
General description
18:0 Diether PC (phosphocholine) is a class of glycerophospholipids that has two octadecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.
Packaging
20 mL Clear Glass Screw Cap Vial (999991P-500mg)
5 mL Amber Glass Screw Cap Vial (999991P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
法规信息
新产品
此项目有
Domain-induced activation of human phospholipase A2 type IIA: local versus global lipid composition.
Chad Leidy et al.
Biophysical journal, 90(9), 3165-3175 (2006-02-08)
Secretory human phospholipase A2 type IIA (PLA2-IIA) catalyzes the hydrolysis of the sn-2 ester bond in glycerolipids to produce fatty acids and lysolipids. The enzyme is coupled to the inflammatory response, and its specificity toward anionic membrane interfaces suggests a
Hitoshi Matsuki et al.
Biochimica et biophysica acta, 1768(3), 479-489 (2006-12-05)
The bilayer phase transitions of a series of ether-linked phospholipids, 1,2-dialkylphosphatidylcholines containing linear saturated alkyl chain (C(n)=12, 14, 16 and 18), were observed by differential scanning calorimetry (DSC) under ambient pressure and light-transmittance measurements under high pressure. The thermodynamic quantities
John M Dean et al.
Protein & cell, 9(2), 196-206 (2017-05-20)
Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether bond, as opposed to an ester bond in the more common diacyl phospholipids. This
Juergen Graessler et al.
PloS one, 4(7), e6261-e6261 (2009-07-16)
Dyslipoproteinemia, obesity and insulin resistance are integrative constituents of the metabolic syndrome and are major risk factors for hypertension. The objective of this study was to determine whether hypertension specifically affects the plasma lipidome independently and differently from the effects
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