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Merck
CN

A-905

α-羟阿普唑仑标准液 溶液

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式(希尔记法):
C17H13ClN4O
化学文摘社编号:
分子量:
324.76
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-659-6
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InChI key

ZURUZYHEEMDQBU-UHFFFAOYSA-N

InChI

1S/C17H13ClN4O/c18-12-6-7-14-13(8-12)17(11-4-2-1-3-5-11)19-9-15-20-21-16(10-23)22(14)15/h1-8,23H,9-10H2

SMILES string

OCc1nnc2CN=C(c3ccccc3)c4cc(Cl)ccc4-n12

grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing
pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

General description

A major urinary metabolite of the benzodiazepine alprazolam. Alprazolam, commonly sold under the trade name Xanax®, is a short-acting anxiolytic approved to treat panic and other anxiety disorders including generalized or social anxiety disorder. This certified Snap-N-Spike® solution standard is suitable for use in LC/MS or GC/MS applications such as forensic analysis, clinical toxicology, urine drug testing, or pain prescription monitoring.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Xanax is a registered trademark of Pharmacia & Upjohn Company

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

监管及禁止进口产品
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Alprazolam, alpha-hydroxy- and 4-hydroxyalprazolam analysis in plasma by high-performance liquid chromatography.
R L Miller et al.
Journal of chromatography, 430(1), 180-186 (1988-08-19)
A J Jenkins et al.
Journal of analytical toxicology, 21(3), 218-220 (1997-05-01)
Alprazolam is one of the most widely prescribed benzodiazepines in the United States. It is generally considered a safe and effective drug for the treatment of anxiety disorders and panic attacks. Few overdoses that are due to the sole ingestion
Annika Allqvist et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 814(1), 127-131 (2004-12-21)
A sensitive and specific method was developed for quantification of alprazolam and its two metabolites 4-hydroxyalprazolam and alpha-hydroxyalprazolam in plasma. The work up procedure was solid phase extraction. Liquid chromatography-mass spectrometry (LC-MS) was used for separation, detection and quantification of
[Pharmacological studies on alprazolam, and its main metabolites, alpha-OH-alprazolam and HB compound (author's transl)].
M Abe et al.
Igaku kenkyu. Acta medica, 50(7), 495-507 (1980-10-01)
A D Fraser et al.
Journal of analytical toxicology, 17(7), 427-431 (1993-11-01)
Adinazolam is a triazolobenzodiazepine, currently under clinical investigation, that possesses antidepressant and anxiolytic activity. It has a short half-life (less than 3 h), and less than 2% of an oral dose is excreted unchanged. The major urinary metabolite is N-desmethyladinazolam

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