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Merck
CN

C-130

可的松标准液 溶液

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式（希尔记法）:
C21H28O5
化学文摘社编号:
53-06-5
分子量:
360.44
MDL number:
MFCD00003610
UNSPSC Code:
41116107
EC Number:
200-659-6
NACRES:
NA.24

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form

liquid

feature

(Snap-N-Spike®)

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

O[C@]1([C@@]2([C@H]([C@H]3[C@@H]([C@]4(CCC(=O)C=C4CC3)C)C(=O)C2)CC1)C)C(=O)CO

InChI key

MFYSYFVPBJMHGN-ZPOLXVRWSA-N

InChI

1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1

grade

certified reference material

Quality Level

300

相关类别

General description

可的松是在肾上腺中产生的一种皮质类固醇。 使用可的松能够在短期内缓解疼痛并减少炎症引起的肿胀。此认证加标溶液®适用于内分泌，临床化学和新生儿筛查LC-MS/MS应用。

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

危险化学品
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[From classical corticotherapy to cortisone loading].
J Arlet
Annales de medecine interne, 145 Suppl 2, 5-10 (1994-06-01)
[50 years cortisone treatment--what has changed?].
H Kaiser
Fortschritte der Medizin, 116(26), 20-22 (1998-11-17)
Hanns Kaiser
Wiener klinische Wochenschrift, 115(1-2), 6-21 (2003-03-28)
Five decades of experimental and clinical experience have changed corticoid therapy thoroughly. Corticoides have two modes of action. The first is a genomic effect through which anti-inflammatory proteins are formed which inhibit pro-inflammatory cytokines. This effect is initiated even by
A Matucci et al.
Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna, 11(3), 187-195 (1996-07-01)
There is general agreement on the inflammatory pathogenesis of bronchial asthma: an accumulation of activated eosinophils, degranulated mast cells, T lymphocytes and in very severe forms, granulocytes has constantly been found in the bronchial mucosa. In allergic bronchial asthma, inflammation
B U Ihle
Anaesthesia and intensive care, 29(2), 155-162 (2001-04-21)
The use of steroids as an adjunct to antimicrobial therapy has been controversial for many decades. Recent reports of the use of steroids in supraphysiological rather than in "industrial" doses in patients with sustained circulatory instability has re-ignited the debate.
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