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Merck
CN

F-013

芬太尼标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式（希尔记法）:
C22H28N2O
化学文摘社编号:
437-38-7
分子量:
336.47
NACRES:
NA.24
PubChem Substance ID:
329799631
UNSPSC Code:
41116107
MDL number:
MFCD00661055

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Quality Level

300

InChI key

PJMPHNIQZUBGLI-UHFFFAOYSA-N

SMILES string

CCC(=O)N(C1CCN(CC1)CCc2ccccc2)c3ccccc3

InChI

1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal), kontrollierte Droge in Deutschland

Gene Information

human ... OPRM1(4988)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

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General description

该认证的溶液标准适用于各种 LC/MS 或 GC/MS 测试应用，包括从法医分析、临床毒理学和止痛处方监测到尿液药物测试和药物研究。

芬太尼属于合成阿片类药物，具有强效的μ-阿片受体激动作用。它以麻醉和镇痛特性而闻名，效力是海洛因的 100 倍。芬太尼以 Duragesic®、Actiq®和Fentora® 等各种商品名出售，在镇痛活性方面比吗啡更有效。

Application

该认证标准溶液（CRM）还可作如下用途：
  • 使用基于液相色谱-串联质谱（LC-MS/MS）的程序对头发样品中芬太尼及其衍生物进行多残留分析
  • 采用高效液相色谱与二极管阵列检测和安培检测的组合分别和同时测定街头检获样品中的海洛因、芬太尼及其 10 种类似物
  • 开发超高效液相色谱-串联质谱（UHPLC-MS/MS）技术来估算头发样品中的 31 种芬太尼类似物和 6 种合成阿片类药物
  • 通过液-液萃取后的液相色谱-串联质谱（LC-MS/MS）对芬太尼及其类似物和合成阿片类药物全血样品进行分离和定量分析
  • 通过纸喷雾-质谱法对尿液和镇痛片浆液中的芬太尼和去芬太尼含量进行半定量分析

Features and Benefits

  • 完全符合 ISO/IEC 17025 和 ISO 17034 认证
  • 附综合分析证书（CoA），包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
  • 通过实时稳定性研究严格测试，以确保准确性和保质期
  • 使用合格的精密天平进行重量准备，以确保最小不确定性
  • 氩气环境下火焰密封，装入安瓿以便长期保存
  • 提供方便的 DEA 豁免格式，以提高实验室效率

Legal Information

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
Actiq is a registered trademark of Anesta Corp.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Duragesic is a registered trademark of Johnson & Johnson
Fentora is a registered trademark of Cima Labs, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

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Intranasal Fentanyl Spray (INFS) was developed for the treatment of breakthrough pain (BTP) in cancer patients using a new route of administration. Dose strengths of 50, 100, and 200 μg INFS (Instanyl®) are currently on the market, however, some adult
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